University Research Lecturer
- British Heart Foundation Intermediate Basic Science Research Fellow
I am interested in disease mechanisms in cardiomyopathies. In particular I want to understand how biomechanical stress can contribute to the pathogenesis of Hypertrophic Cardiomyopathy.
Age- and strain-related aberrant Ca2+ release is associated with sudden cardiac death in the ACTC E99K mouse model of hypertrophic cardiomyopathy.
Rowlands CT. et al, (2017), Am J Physiol Heart Circ Physiol, 313, H1213 - H1226
Mammalian γ2 AMPK regulates intrinsic heart rate.
Yavari A. et al, (2017), Nat Commun, 8
When signalling goes wrong: pathogenic variants in structural and signalling proteins causing cardiomyopathies.
Ehsan M. et al, (2017), J Muscle Res Cell Motil, 38, 303 - 316
Insights into disease mechanisms of cardiomyopathy in the presence of the CSRP3 C58G mutation
Ehsan M. et al, (2017)
Evidence for Chaperone Function in Mechanosensation
Collier M. et al, (2017), BIOPHYSICAL JOURNAL, 112, 491A - 491A