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Contact information

Email
katja.gehmlich@cardiov.ox.ac.uk

Research groups

DPhil projects available

Engineered induced pluripotent stem cell lines for phenotypic selection of cardiac cell types

Exploring the role of Z-disk structure and signalling for striated muscle integrity with the help of genome-edited mouse models of cardiomyopathy

Katja Gehmlich

Associate Professor of Cardiovascular Science

British Heart Foundation Intermediate Basic Science Research Fellow

I am interested in disease mechanisms in cardiomyopathies. In particular I want to understand how biomechanical stress can contribute to the pathogenesis of Hypertrophic Cardiomyopathy.

Recent publications

HspB1 phosphorylation regulates its intramolecular dynamics and mechanosensitive molecular chaperone interaction with filamin C.
Journal article

Collier MP. et al, (2019), Sci Adv, 5
Mutant Muscle LIM Protein C58G causes cardiomyopathy through protein depletion.
Journal article

Ehsan M. et al, (2018), J Mol Cell Cardiol, 121, 287 - 296
Non-sarcomeric causes of heart failure.
Journal article

Gehmlich K. and Ehler E., (2018), Biophys Rev
Genetics of and pathogenic mechanisms in arrhythmogenic right ventricular cardiomyopathy.
Journal article

Vimalanathan AK. et al, (2018), Biophys Rev
Age- and strain-related aberrant Ca2+ release is associated with sudden cardiac death in the ACTC E99K mouse model of hypertrophic cardiomyopathy.
Journal article

Rowlands CT. et al, (2017), Am J Physiol Heart Circ Physiol, 313, H1213 - H1226

More publications