Contact information
DPHIL SUPERVISOR PROFILE
Gillian Douglas
PhD
Associate Professor of Cardiovascular Science
Large studies linking common variations to the occurrence of coronary artery disease have enabled us to identify several new genes that may have a causative influence on the susceptibility to developing coronary artery disease. However, for many of these genes the mechanism by which they alter cardiovascular disease pathology is unknown.
Recent publications
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PHACTR1 modulates vascular compliance but not endothelial function: a translational study.
Journal article
Wood A. et al, (2022), Cardiovasc Res
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Endothelial GTPCH (GTP Cyclohydrolase 1) and Tetrahydrobiopterin Regulate Gestational Blood Pressure, Uteroplacental Remodeling, and Fetal Growth.
Journal article
Chuaiphichai S. et al, (2021), Hypertension
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Developmental role of PHD2 in the pathogenesis of pseudohypoxic pheochromocytoma.
Journal article
Eckardt L. et al, (2021), Endocr Relat Cancer, 28, 757 - 772
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A key role for the novel coronary artery disease gene JCAD in atherosclerosis via shear stress mechanotransduction.
Journal article
Douglas G. et al, (2020), Cardiovasc Res, 116, 1863 - 1874
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Insulin-induced vascular redox dysregulation in human atherosclerosis is ameliorated by dipeptidyl peptidase 4 inhibition.
Journal article
Akoumianakis I. et al, (2020), Sci Transl Med, 12