Professor of Stroke Medicine
- Chief Executive Officer, Oxford Academic Health Science Network
- Consultant Stroke Physician OUH
My work focuses on developing and evaluating treatments that can reduce brain damage in the first few hours after stroke, and developing better processes of care to deliver for stroke patients.
I have developed and evaluated the performance of stroke recognition instruments such as the Face Arm Speech Test (FAST) and Recognition of Stroke in the Emergency Room Scale (ROSIER) to improve early diagnosis of stroke by the public, ambulance paramedics and Emergency Department teams.
My work has evaluated the risks and benefits of thrombolysis in very elderly stroke patients 80 years or older, who are the population at highest risk of stroke.
In addition to my research in stroke my work more broadly seeks to understand the risks and benefits of drug therapies in older people.
Paramedic experiences of using an enhanced stroke assessment during a cluster randomised trial: a qualitative thematic analysis.
Lally J. et al, (2020), Emerg Med J
Platelet function/reactivity testing and prediction of risk of recurrent vascular events and outcomes after TIA or ischaemic stroke: systematic review and meta-analysis.
Lim ST. et al, (2020), J Neurol
Rapid mobilisation of research in response to covid-19: a paradigm for the future.
James M. et al, (2020), BMJ : British Medical Journal, 369
Effect of Antihypertensive Medication Reduction vs Usual Care on Short-term Blood Pressure Control in Patients With Hypertension Aged 80 Years and Older: The OPTIMISE Randomized Clinical Trial.
Sheppard JP. et al, (2020), JAMA, 323, 2039 - 2051
An extended stroke rehabilitation service for people who have had a stroke: the EXTRAS RCT.
Shaw L. et al, (2020), Health Technol Assess, 24, 1 - 202