Oxford Haemophilia & Thrombosis Centre; NIHR Oxford Biomedical Research Centre
University of Aberdeen; Thrombosis & Haemostasis laboratory
My main research interest lies in fibrinolysis and how clot structure alters the rate of lysis. I am currently working with Dr Nicola Curry and her team of clinicians at the Oxford Haemophilia and Thrombosis Centre at the Churchill Hospital.
My work focuses on two different types of fibrinogen replacement administered to trauma patients. Fibrinogen is the key pro-coagulant factor required for stable clot formation. Patients recruited to the Fibrinogen Early in Severe Trauma StudY (FEISTY) were given one of two treatments: cryoprecipitate or fibrinogen concentrate. My research investigates the differences in clot structure and strength between the two fibrinogens, and how this correlates with clinical outcome.
Morrow, G.B., C.S. Whyte, and N.J. Mutch, Functional plasminogen activator inhibitor 1 is retained on the activated platelet membrane following platelet activation. Haematologica, 2019. Doi:10.3324/haematol.2019.230367