Gael Morrow

Research Fellow

My main research interest lies in fibrinolysis (degradation of a blood clot) and how the clot structure alters the rate of lysis. I am currently working with Dr Nicola Curry and her team of clinicians at the Oxford Haemophilia and Thrombosis Centre at the Churchill Hospital.

My work focuses on two different types of fibrinogen replacement administered to trauma patients. Fibrinogen is the key pro-coagulant factor required for stable clot formation. Patients recruited to the Fibrinogen Early in Severe Trauma StudY (FEISTY) were given one of two treatments: cryoprecipitate or fibrinogen concentrate. My research investigates the differences in clot structure and strength between the two fibrinogens, and how this correlates with clinical outcome.

Recent publications

A serpin with a finger in many PAI’s: PAI-1’s central function in thromboinflammation and cardiovascular disease
Journal article

MORROW G. et al, (2021), Frontiers in Cardiovascular Medicine
Fibrinogen Replacement Therapy for Traumatic Coagulopathy: Does the Fibrinogen Source Matter?
Journal article

Morrow GB. et al, (2021), Int J Mol Sci, 22
Characterisation of a novel thrombomodulin c.1487delC,p.(Pro496Argfs*10) variant and evaluation of therapeutic strategies to manage the rare bleeding phenotype.
Journal article

Morrow GB. et al, (2021), Thromb Res, 197, 100 - 108
Exposure of plasminogen and the novel plasminogen receptor, Plg-RKT, on activated human and murine platelets
Journal article

Whyte CS. et al, (2020), Blood
Coagulation status of critically ill patients with and without liver disease assessed using a novel thrombin generation analyzer.
Journal article

Morrow GB. et al, (2020), J Thromb Haemost, 18, 1576 - 1585
Fibrinolytic abnormalities in acute respiratory distress syndrome (ARDS) and versatility of thrombolytic drugs to treat COVID-19.
Journal article

Whyte CS. et al, (2020), J Thromb Haemost
Functional plasminogen activator inhibitor 1 is retained on the activated platelet membrane following platelet activation
Journal article

Morrow GB. et al, (2019), Haematologica, haematol.2019.230367 - haematol.2019.230367
Coagulation status of critically ill patients with liver disease assessed using a novel thrombin generation analyser
Conference paper

Morrow GB. et al, (2019), BRITISH JOURNAL OF HAEMATOLOGY, 185, 137 - 137
UTP is not a biased agonist at human P2Y11 receptors
Journal article

Morrow GB. et al, (2014), Purinergic Signalling, 10, 581 - 585

More publications