Contact information
RESEARCH GROUPS
Oxford Haemophilia & Thrombosis Centre; NIHR Oxford Biomedical Research Centre
University of Aberdeen; Thrombosis & Haemostasis laboratory
https://www.abdn.ac.uk/people/gael.morrow1
Gael Morrow
Post-doctoral researcher
My main research interest lies in fibrinolysis (degradation of a blood clot) and how the clot structure alters the rate of lysis. I am currently working with Dr Nicola Curry and her team of clinicians at the Oxford Haemophilia and Thrombosis Centre at the Churchill Hospital.
My work focuses on two different types of fibrinogen replacement administered to trauma patients. Fibrinogen is the key pro-coagulant factor required for stable clot formation. Patients recruited to the Fibrinogen Early in Severe Trauma StudY (FEISTY) were given one of two treatments: cryoprecipitate or fibrinogen concentrate. My research investigates the differences in clot structure and strength between the two fibrinogens, and how this correlates with clinical outcome.
Recent publications
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Characterisation of a novel thrombomodulin c.1487delC,p.(Pro496Argfs*10) variant and evaluation of therapeutic strategies to manage the rare bleeding phenotype.
Journal article
Morrow GB. et al, (2020), Thromb Res, 197, 100 - 108
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Exposure of plasminogen and the novel plasminogen receptor, Plg-RKT, on activated human and murine platelets
Journal article
Whyte CS. et al, (2020), Blood
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Coagulation status of critically ill patients with and without liver disease assessed using a novel thrombin generation analyzer.
Journal article
Morrow GB. et al, (2020), J Thromb Haemost, 18, 1576 - 1585
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Fibrinolytic abnormalities in acute respiratory distress syndrome (ARDS) and versatility of thrombolytic drugs to treat COVID-19.
Journal article
Whyte CS. et al, (2020), J Thromb Haemost
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Functional plasminogen activator inhibitor 1 is retained on the activated platelet membrane following platelet activation
Journal article
Morrow GB. et al, (2019), Haematologica, haematol.2019.230367 - haematol.2019.230367
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Coagulation status of critically ill patients with liver disease assessed using a novel thrombin generation analyser
Conference paper
Morrow GB. et al, (2019), BRITISH JOURNAL OF HAEMATOLOGY, 185, 137 - 137
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UTP is not a biased agonist at human P2Y11 receptors
Journal article
Morrow GB. et al, (2014), Purinergic Signalling, 10, 581 - 585