Postdoctoral Research Assistant
I am a postdoctoral research assistant interested in biophysical modelling of the liver tissue both in healthy individuals and in patients with non-alcoholic fatty liver disease (NAFLD). During my DPhil I have characterised the effects of fat, glycogen and hydration status on quantitative imaging methods with magnetic resonance imaging.
Currently I'm interested in developing imaging methods and protocols that will allow the reduction and eventual elimination of liver biopsies in patients with NAFLD. The relationship between basic liver physiology and quantitative MRI measurements is still not fully described, therefore I am also devising experiments that allow the probing of liver physiology at different stages of the diurnal cycle and in various metabolic states.
Being part of the Liver Investigation: Testing Marker Utility in Steatohepatitis (LITMUS) community allows me to also participate in investigating the diagnostic performance of non-invasive tests (both imaging- and blood-based) in identifying liver scarring in patients with NAFLD. I am focusing on evaluating diagnostic test performance in prospective cohorts as well as in a large retrospective group of patients collated with the help international collaborators.
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A low-energy total diet replacement programme demonstrates a favourable safety profile and improves liver disease severity in non-alcoholic steatohepatitis
KOUTOUKIDIS D. et al, (2023), Obesity
Noninvasive assessment of steatosis and viability of cold-stored human liver grafts by MRI.
Young LAJ. et al, (2021), Magn Reson Med
Editorial for "Assessment of Imaging Modalities Against Liver Biopsy in Nonalcoholic Fatty Liver Disease: The Amsterdam NAFLD-NASH Cohort".
Hockings PD. et al, (2021), J Magn Reson Imaging
Diagnostic accuracy of non-invasive tests for advanced fibrosis in patients with NAFLD: an individual patient data meta-analysis
Mózes FE. et al, (2021), Gut