Contact information

Christian Babbs

BSc (Hons) DPhil

Head of Genome Engineering

Generating genetically altered models for the research community

I lead the Geneome Engineering, Transgenics and Virus Production facility at the WIMM. We generate all reagents for genome engineering. We also modify embryonic stem cells and 1-cell embryos for rapid production of model systems.

Key publications

TR-16 syndrome: mechanisms linking monosomy to phenotype.

Babbs C. et al, (2020), J Med Genet, 57, 414 - 421

Genetic dissection of the α-globin super-enhancer in vivo.

Hay D. et al, (2016), Nat Genet, 48, 895 - 903

Factors influencing success of clinical genome sequencing across a broad spectrum of disorders.

Taylor JC. et al, (2015), Nat Genet, 47, 717 - 726

De novo and rare inherited mutations implicate the transcriptional coregulator TCF20/SPBP in autism spectrum disorder.

Babbs C. et al, (2014), J Med Genet, 51, 737 - 747

Homozygous mutations in a predicted endonuclease are a novel cause of congenital dyserythropoietic anemia type I.

Babbs C. et al, (2013), Haematologica, 98, 1383 - 1387

Recent publications

Using Patient Feedback to Improve Treatment Outcomes for Patients with Congenital Dyserythropoietic Anaemia Type I Receiving Interferon Therapy.

Frey K. et al, (2026), J Clin Med, 15

ncient genomic linkage of α-globin and Nprl3 couples metabolism with erythropoiesis.

Preston AE. et al, (2025), Nat Commun, 16

Correction: The α-globin super-enhancer acts in an orientation-dependent manner.

Kassouf MT. et al, (2025), Nat Commun, 16

The α-globin super-enhancer acts in an orientation-dependent manner.

Kassouf MT. et al, (2025), Nat Commun, 16

Erythropoiesis in the human

Higgs DR. et al, (2025), 43 - 55

More publications

ORCID

0000-0002- 1898-5878

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Contact information

Christian Babbs

Key publications

Recent publications

ORCID