Colleges
Kendrick Yiu
BSc (Hons), MRes
DPhil Student
Cardiac Fibrosis and Atrial Fibrillation
I am a DPhil student in Medical Sciences with an interest in cardiovascular medicine and translational research. With a background in Biomedical Sciences and a Master's in Clinical Research, my work bridges fundamental science and clinical applications.
My DPhil research strives to decipher molecular mechanisms that drive fibrosis and structural remodelling in atrial fibrillation. In particular, I use human cardiac fibroblasts as a model to better understand their role in fibrogenesis. Beyond my core research, I contribute to a range of collaborative projects, including clinical biomarker studies, multiomics approaches (transcriptomics and proteomics), and miRNA biology.
My goal is to unravel the molecular landscape of atrial fibrillation and translate discoveries into novel therapeutic strategies for patients.
Recent publications
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Single-nucleus multi-omics implicates androgen receptor signaling in cardiomyocytes and NR4A1 regulation in fibroblasts during atrial fibrillation.
Leblanc FJA. et al, (2025), Nat Cardiovasc Res
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Aging-associated mechanisms of atrial fibrillation progression and their therapeutic potential
Zhao S. et al, (2024), Journal of Cardiovascular Aging, 4
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Atrial proteomic profiling reveals a switch towards profibrotic gene expression program in CREM-IbΔC-X mice with persistent atrial fibrillation.
Zhao S. et al, (2024), J Mol Cell Cardiol, 190, 1 - 12