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Research Projects Available

Dphil in cardiovascular science

Technology, Artificial Intelligence, and Data Driven Solutions for Cardiovascular and Metabolic Disease

DPhil in medical sciences opportunities will appear below:

MSc by Research in medical sciences opportunities will appear below:

Betty Raman

MBBS DPhil FESC FRACP


Associate Professor of Cardiovascular Medicine

  • NIHR South Central RRDN Cardiology Specialty Lead
  • Hon. Consultant Cardiologist (Loc)
  • Oxford Programme Director of BHF Doctoral Training Programme on Technology, Data and AI (Imperial-Oxford DTP)
  • Wellcome Career Development Award Fellow
  • RDM Cardiovascular Medicine EDI Champion

Prof Betty Raman is a senior honorary consultant cardiologist specialising in advanced cardiovascular imaging (CMR and cardiac CT) and inherited and cardiomyopathic heart disease. She leads a translational research programme in monogenic (e.g., HCM, DCM etc) and polygenic cardiac (hypertensive heart diseases, cardiometabolic etc.) diseases that bridge mechanistic discovery, clinical application, and innovation in drug development.

After completing her specialist cardiology training in Australia (FRACP), she joined the University of Oxford in 2015 to pursue a DPhil in hypertrophic cardiomyopathy, the leading cause of sudden cardiac death in young adults and athletes. Her doctoral work led to the development of a novel oxygen sensitive magnetic resonance method that detects myocardial hypoxia non-invasively and holds promise as an early biomarker of disease activity. This pioneering work has been recognised internationally through awards from the ESC, AHA, BSCMR, SCMR, and BCS.

Building on this foundation, she was awarded a British Heart Foundation Transition Fellowship (2020) and subsequently a Wellcome Career Development Award (2024) to advance a multidisciplinary research programme integrating imaging, genetics, energetics, and computational modelling. Her goal is to identify and validate early markers of disease progression in hypertrophic (e.g., HCM) and related cardiomyopathies, enabling more precise risk prediction and supporting evaluation of emerging therapies.

During the COVID 19 pandemic, she led the C-MORE study, a large multicentre initiative that combined MRI, cardiopulmonary exercise testing, and cognitive assessments to characterise the long term multi organ consequences of COVID 19. This work helped shape understanding of post-viral cardiovascular and systemic recovery.

Her current research focuses on:

  1. Early stage disease detection and monitoring in cardiomyopathies using next generation CMR including BOLD, DTI, spectroscopy, and radiomics.

  2. Mechanistic biomarkers to support early phase and adaptive clinical trials.

  3. Cross organ interactions in cardiometabolic disease, integrating heart, brain, liver, and renal imaging.

As a senior academic leader, she collaborates widely across academia, the NHS, and industry to translate advanced imaging into clinical and commercial impact. She actively welcomes scientific collaborators, students, and industrial partners interested in biomarker discovery, imaging enabled trial design, and AI based modelling for cardiovascular disease.

Recent publications

Recombinant shingles vaccination and the risk of cardiovascular events.

Journal article

Corsi-Zuelli F. et al, (2026), Nat Med

Late Gadolinium Enhancement in Nonischemic Dilated Cardiomyopathy.

Journal article

Raman B. and Prasad SK., (2026), Circulation, 154, 512 - 516

Trientine for hypertrophic cardiomyopathy: a phase 2 trial.

Journal article

Farrant JP. et al, (2026), Eur Heart J

Non-invasive pressure-volume loop analysis in left ventricular load manipulation.

Journal article

Pola K. et al, (2026), Clin Physiol Funct Imaging, 46

Predictors of Long-Term Outcomes in Hypertrophic Cardiomyopathy: The NHLBI HCM Registry.

Journal article

HCMR Investigators . et al, (2026), JAMA

Biobank-Scale Plasma Proteomics Identifies Novel Biomarkers in Hypertrophic Cardiomyopathy.

Journal article

Chan JH. et al, (2026), Circ Genom Precis Med

HFpEF and MASLD: converging mechanisms and clinical implications.

Journal article

Capone F. et al, (2026), Nat Rev Cardiol

Evaluating Acute Ischemic Myocardial Injury With Photon-Counting Computed Tomography.

Journal article

Kotronias RA. et al, (2026), JACC Cardiovasc Imaging, 19, 284 - 287

Comparison of cardiac diffusion MRI using multiple prospective respiratory motion correction techniques.

Journal article

Jermy S. et al, (2026), Magn Reson Med, 95, 442 - 456

Sleep apnea at the frontier- an integrated multidisciplinary functional framework.

Journal article

Beache GM. et al, (2025), Sleep Med Rev, 84

Human genetics implicate thromboembolism in the pathogenesis of long COVID in individuals of European ancestry.

Journal article

Schuermans A. et al, (2025), Nat Cardiovasc Res, 4, 1662 - 1676

Computational modelling of myocardial metabolism in patients with advanced heart failure.

Journal article

Beyhoff N. et al, (2025), Eur J Heart Fail, 27, 3411 - 3422

Prospective electrocardiographic and cardiovascular magnetic resonance alterations in the UK Biobank coronavirus disease 2019 repeat imaging study.

Journal article

Chadalavada S. et al, (2025), Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance, 27

Multi-center investigation of cardiac diffusion tensor imaging in healthy volunteers by the Society of Cardiovascular Magnetic Resonance Cardiac Diffusion Special Interest Group NETwork (SIGNET).

Journal article

Teh I. et al, (2025), Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance, 27

Subclinical Postpartum Renal Structure After Hypertensive Pregnancy Disorders.

Journal article

Cutler HR. et al, (2025), Hypertension, 82, 1948 - 1958

Sex Differences in the Genetic Causes of Dilated Cardiomyopathy.

Journal article

Mangino M. et al, (2025), J Am Coll Cardiol, 86, 400 - 403

Could CT radiomics be the new frontier for myocardial tissue characterization in cardiomyopathies?

Journal article

Raman B. and Clarke N., (2025), Eur Heart J Cardiovasc Imaging, 26, 1049 - 1050

Multiorgan Imaging for Interorgan Crosstalk in Cardiometabolic Diseases.

Journal article

Devesa A. et al, (2025), Circ Res, 136, 1454 - 1475

Considerations for drug trials in hypertrophic cardiomyopathy.

Journal article

Farrant JP. et al, (2025), ESC Heart Fail, 12, 1095 - 1112

Demographic-Based Personalized Left Ventricular Hypertrophy Thresholds for Hypertrophic Cardiomyopathy Diagnosis.

Journal article

Shiwani H. et al, (2025), J Am Coll Cardiol, 85, 685 - 695

Myocardial disarray and fibrosis across hypertrophic cardiomyopathy stages associate with ECG markers of arrhythmic risk.

Journal article

Ashkir Z. et al, (2025), Eur Heart J Cardiovasc Imaging, 26, 218 - 228

Contrast-Free Myocardial Scar Segmentation in Cine MRI using Motion and Texture Fusion

Conference paper

Yang G. et al, (2025), Proceedings - International Symposium on Biomedical Imaging

Postpartum imaging of renal structure following hypertensive and normotensive pregnancy

Conference paper

Cutler H. et al, (2025), EUROPEAN HEART JOURNAL, 46

GENETIC ASSOCIATION OF CLONAL HEMATOPOIESIS WITH NON-ISCHEMIC CARDIAC DISEASE AND ADVERSE REMODELING

Journal article

Morley A. et al, (2025), JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 85, 330 - 330

Effects of software on myocardial T1 measurements: A 3 T multicentre single vendor phantom study

Conference paper

Atkinson D. et al, (2025), Journal of Cardiovascular Magnetic Resonance, 27, 101653 - 101653

1H and 31P MR Spectroscopy to Assess Muscle Mitochondrial Dysfunction in Long COVID.

Journal article

Finnigan LEM. et al, (2024), Radiology, 313

1H and 31P MR Spectroscopy to Assess Muscle Mitochondrial Dysfunction in Long COVID

Journal article

Finnigan LEM. et al, (2024), Radiology, 313

Clinical Significance of Myocardial Injury in Patients Hospitalized for COVID-19: A Prospective, Multicenter, Cohort Study.

Journal article

Shiwani H. et al, (2024), JACC Cardiovasc Imaging, 17, 1320 - 1331

Differentiating Left Ventricular Remodeling in Aortic Stenosis From Systemic Hypertension.

Journal article

Mahmod M. et al, (2024), Circ Cardiovasc Imaging, 17

Mechanisms of ischaemia-induced arrhythmias in hypertrophic cardiomyopathy: a large-scale computational study.

Journal article

Coleman JA. et al, (2024), Cardiovasc Res, 120, 914 - 926

The complexity of cardiovascular long COVID: where we are.

Journal article

Gandhi RS. and Raman B., (2024), Cardiovasc Res, 120, e30 - e32

Flow inefficiencies in non-obstructive HCM revealed by kinetic energy and hemodynamic forces on 4D-flow CMR.

Journal article

Pola K. et al, (2024), Eur Heart J Imaging Methods Pract, 2

Long COVID and cardiovascular disease: a prospective cohort study.

Journal article

Lawson CA. et al, (2024), Open Heart, 11

Personalizing Apical Hypertrophic Cardiomyopathy Diagnosis: A Major Step Forward, but Challenges Remain.

Journal article

Raman B., (2024), JACC Cardiovasc Imaging, 17, 513 - 515

Synbiotics in post-acute COVID-19 syndrome-a potential new treatment framework?

Journal article

Raman B. and Ramasamy MN., (2024), Lancet Infect Dis, 24, 219 - 221

Cohort Profile: Post-Hospitalisation COVID-19 (PHOSP-COVID) study.

Journal article

Elneima O. et al, (2024), Int J Epidemiol, 53

Cohort Profile: Post-Hospitalisation COVID-19 (PHOSP-COVID) study.

Journal article

Elneima O. et al, (2024), International journal of epidemiology, 53

Accelarated immune ageing is associated with COVID-19 disease severity.

Journal article

Lord JM. et al, (2024), Immun Ageing, 21

Effects of ranolazine on the arrhythmic substrate in hypertrophic cardiomyopathy.

Journal article

Coleman JA. et al, (2024), Front Pharmacol, 15

ECG Deep Learning Dissects Physiology of Hypertrophic Cardiomyopathy

Conference paper

Manohar S. et al, (2024), Computing in Cardiology, 51

Long term effects of COVID-19 on the oral and lower airway microbiota

Conference paper

Headley DADL. et al, (2024), EUROPEAN RESPIRATORY JOURNAL, 64

Physical performance 5 and 12 months after hospital-discharge in CCVID-19 survivors

Conference paper

Baldwin MM. et al, (2024), EUROPEAN RESPIRATORY JOURNAL, 64

Association between SARC-F status and long-term physical function after COVID-19 hospitalisation

Conference paper

Mills G. et al, (2024), EUROPEAN RESPIRATORY JOURNAL, 64

Balancing the value and risk of exercise-based therapy post-COVID-19: a narrative review.

Journal article

Singh SJ. et al, (2023), Eur Respir Rev, 32

Liver disease is a significant risk factor for cardiovascular outcomes - A UK Biobank study.

Journal article

Roca-Fernandez A. et al, (2023), J Hepatol, 79, 1085 - 1095

Long COVID research: an update from the PHOSP-COVID Scientific Summit.

Journal article

Brightling CE. et al, (2023), Lancet Respir Med, 11, e93 - e94

Multiorgan MRI findings after hospitalisation with COVID-19 in the UK (C-MORE): a prospective, multicentre, observational cohort study.

Journal article

C-MORE/PHOSP-COVID Collaborative Group ., (2023), Lancet Respir Med, 11, 1003 - 1019

Mechanisms and prognostic impact of myocardial ischaemia in hypertrophic cardiomyopathy.

Journal article

Coleman JA. et al, (2023), Int J Cardiovasc Imaging, 39, 1979 - 1996

Rationale and design of a randomised trial of trientine in patients with hypertrophic cardiomyopathy.

Journal article

Farrant J. et al, (2023), Heart, 109, 1175 - 1182

Left ventricular anatomy in obstructive hypertrophic cardiomyopathy: beyond basal septal hypertrophy.

Journal article

Hermida U. et al, (2023), Eur Heart J Cardiovasc Imaging, 24, 807 - 818

Myocardial Injury on CMR in Patients With COVID-19 and Suspected Cardiac Involvement.

Journal article

Vidula MK. et al, (2023), JACC Cardiovasc Imaging, 16, 609 - 624

3-Dimensional Strain Analysis of Hypertrophic Cardiomyopathy: Insights From the NHLBI International HCM Registry.

Journal article

Heydari B. et al, (2023), JACC Cardiovasc Imaging, 16, 478 - 491

Residual Lung Abnormalities after COVID-19 Hospitalization: Interim Analysis of the UKILD Post-COVID-19 Study.

Journal article

Stewart I. et al, (2023), Am J Respir Crit Care Med, 207, 693 - 703

Long COVID: mechanisms, risk factors and recovery.

Journal article

Astin R. et al, (2023), Exp Physiol, 108, 12 - 27

Acute changes in myocardial tissue characteristics during hospitalization in patients with COVID-19.

Journal article

Shanmuganathan M. et al, (2023), Front Cardiovasc Med, 10

Editorial: Post-COVID-19 cardiovascular sequelae.

Journal article

Condurache D-G. et al, (2023), Front Cardiovasc Med, 10

ABNORMAL SKELETAL METABOLISM BUT NOT CARDIAC DYSFUNCTION AS A CAUSE FOR FATIGUE POST COVID-19

Conference paper

Cassar MP. et al, (2023), JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 81, 1397 - 1397

Post-Hospitalisation COVID-19 (PHOSP-COVID): a prospective multi-centre UK cohort study

Conference paper

Elneima O. et al, (2023), EUROPEAN RESPIRATORY JOURNAL, 62

Cardiovascular disease and mortality sequelae of COVID-19 in the UK Biobank.

Journal article

Raisi-Estabragh Z. et al, (2022), Heart, 109, 119 - 126

Multi-organ imaging demonstrates the heart-brain-liver axis in UK Biobank participants.

Journal article

McCracken C. et al, (2022), Nat Commun, 13

Differing Impact of Preterm Birth on the Right and Left Atria in Adulthood.

Journal article

Schuermans A. et al, (2022), J Am Heart Assoc, 11

Lung Abnormalities Detected with Hyperpolarized 129Xe MRI in Patients with Long COVID.

Journal article

Grist JT. et al, (2022), Radiology, 305, 709 - 717

Altered lung physiology in two cohorts after COVID-19 infection as assessed by computed cardiopulmonography.

Journal article

Magor-Elliott SRM. et al, (2022), J Appl Physiol (1985), 133, 1175 - 1191

Role of Trientine in Hypertrophic Cardiomyopathy: A Review of Mechanistic Aspects.

Journal article

Ramli FF. et al, (2022), Pharmaceuticals (Basel), 15

Postvaccine Myocarditis: A Risk Worth the Reward?

Journal article

Raman B. and Neubauer S., (2022), Radiology, 304, 563 - 565

Long COVID: post-acute sequelae of COVID-19 with a cardiovascular focus.

Journal article

Raman B. et al, (2022), Eur Heart J, 43, 1157 - 1172

Divergent trajectories of antiviral memory after SARS-CoV-2 infection.

Journal article

Tomic A. et al, (2022), Nat Commun, 13

Four-dimensional flow cardiac magnetic resonance assessment of left ventricular diastolic function.

Journal article

Ashkir Z. et al, (2022), Front Cardiovasc Med, 9

Persistence of inflammatory and vascular damage mediators 5 months after acute COVID-19

Conference paper

Petousi N. et al, (2022), EUROPEAN RESPIRATORY JOURNAL, 60

Maximal Wall Thickness Measurement in Hypertrophic Cardiomyopathy: Biomarker Variability and its Impact on Clinical Care.

Journal article

Captur G. et al, (2021), JACC Cardiovasc Imaging, 14, 2123 - 2134

Association of Preterm Birth With Myocardial Fibrosis and Diastolic Dysfunction in Young Adulthood.

Journal article

Lewandowski AJ. et al, (2021), J Am Coll Cardiol, 78, 683 - 692

Predicting the Future From Scars of the Past.

Journal article

Raman B. and Kramer CM., (2021), JACC Cardiovasc Imaging, 14, 959 - 961

Late Breaking Abstract - Breathlessness post COVID-19 despite improvement in cardiopulmonary health

Conference paper

Cassar MP. et al, (2021), EUROPEAN RESPIRATORY JOURNAL, 58

Magnetic resonance imaging

Patent

HESS A. et al, (2020)

British Cardiovascular Society Young Investigator Award 2019.

Journal article

Page DJ. et al, (2019), Heart, 105, 1841 - 1842

Histological Evidence for Impaired Myocardial Perfusion Reserve in Severe Aortic Stenosis.

Journal article

Mahmod M. et al, (2019), JACC Cardiovasc Imaging, 12, 2276 - 2278

Localized rest and stress human cardiac creatine kinase reaction kinetics at 3 T.

Journal article

Clarke WT. et al, (2019), NMR Biomed, 32

Identification of Myocardial Disarray in Patients With Hypertrophic Cardiomyopathy and Ventricular Arrhythmias.

Journal article

Ariga R. et al, (2019), J Am Coll Cardiol, 73, 2493 - 2502

Progression of myocardial fibrosis in hypertrophic cardiomyopathy: mechanisms and clinical implications.

Journal article

Raman B. et al, (2019), Eur Heart J Cardiovasc Imaging, 20, 157 - 167

ENDOTHELIAL LOSS AS A CAUSE OF IMPAIRED MYOCARDIAL PERFUSION RESERVE IN SEVERE AORTIC STENOSIS

Conference paper

Chan K. et al, (2019), HEART, 105, A100 - A101

RV FUNCTION DETERIORATES EARLIER THAN LV FUNCTION AND PREDICTS ADVERSE CARDIOVASCULAR OUTCOMES

Conference paper

Raman B. et al, (2019), HEART, 105, A5 - A6

Progression of myocardial fibrosis in hypertrophic cardiomyopathy: Mechanisms and clinical implications.

Journal article

RAMAN B. et al, (2018), EHJ Cardiovascular Imaging / European Heart Journal - Cardiovascular Imaging

Nitrosative Stress as a Modulator of Inflammatory Change in a Model of Takotsubo Syndrome.

Journal article

Surikow SY. et al, (2018), JACC Basic Transl Sci, 3, 213 - 226

Development of Therapeutic Strategies for Takotsubo Syndrome: Insights From a Rat Model

Conference paper

Surikow SY. et al, (2017), CIRCULATION, 136

Can Perhexiline Be Utilized Without Long-Term Toxicity? A Clinical Practice Audit.

Journal article

Phuong H. et al, (2016), Ther Drug Monit, 38, 73 - 78

Evidence of nitrosative stress within hearts of patients dying of Tako-tsubo cardiomyopathy.

Journal article

Surikow SY. et al, (2015), Int J Cardiol, 189, 112 - 114

Troponin positive patients with unobstructed coronaries: incremental value of cardiovascular magnetic resonance

Conference paper

Raman B. et al, (2015), EUROPEAN HEART JOURNAL, 36, 380 - 380

Nitric Oxide Plays a Janus Role in the Pathogenesis of Tako-tsubo Cardiomyopathy

Conference paper

Nguyen TH. et al, (2015), CIRCULATION, 132

Determinants of shock and mortality in Takotsubo cardiomyopathy: a cohort study

Conference paper

Chong C-R. et al, (2015), EUROPEAN HEART JOURNAL, 36, 1177 - 1178

Recurrent pulmonary oedema after percutaneous radiofrequency renal denervation.

Journal article

Raman B. et al, (2014), Int J Cardiol, 174, e42 - e43

Takotsubo cardiomyopathy presenting as S-T elevation myocardial infarction: not gone but forgotten?

Journal article

Raman B. et al, (2014), Int J Cardiol, 172, e261 - e262

Clopidogrel "resistance": pre- vs post-receptor determinants.

Journal article

Hurst NL. et al, (2013), Vascul Pharmacol, 59, 152 - 161

Not such a rarity: takotsubo cardiomyopathy as a mimic of ST elevation myocardial infarction

Conference paper

Raman B. et al, (2013), EUROPEAN HEART JOURNAL, 34, 539 - 539

Stress cardiomyopathy: new clinical and pathogenetic insights

Conference paper

Horowitz JD. et al, (2013), CARDIOLOGY, 126, 403 - 403

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