My research in Professor Charalambos Antoniades’s group was focused on signaling pathways that regulate myocardial redox state. Previous work in our group has shown that myocardial redox state is regulated by adipokines like adiponectin, and myocardial redox state is associated with post-operative outcomes. During my DPhil, which I completed in our group, I examined the crosstalk between myocardial redox state and hydrogen sulfide biology.
The era of cardiovascular epigenetics: histone deacetylases and vascular inflammation.
Tarun A. and Antoniades C., (2018), Cardiovasc Res, 114, 928 - 930
Perivascular adipose tissue as a regulator of vascular disease pathogenesis: identifying novel therapeutic targets.
Akoumianakis I. et al, (2017), Br J Pharmacol, 174, 3411 - 3424
Mutual Regulation of Epicardial Adipose Tissue and Myocardial Redox State by PPAR-γ/Adiponectin Signalling.
Antonopoulos AS. et al, (2016), Circ Res, 118, 842 - 855
Phosphatidylcholine transfer protein interacts with thioesterase superfamily member 2 to attenuate insulin signaling.
Ersoy BA. et al, (2013), Sci Signal, 6