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The Oxford Centre for Diabetes, Endocrinology and Metabolism (OCDEM) is a pioneering centre that combines clinical care, research and education in diabetes, endocrine and metabolic diseases.

© Martin Phelps

By promoting world-class research, we aim to enhance understanding of these diseases and to accelerate the search for new treatments and cures. We are one of the largest dedicated research centres in diabetes, endocrinology and metabolism in Europe, hosting a large number of world-leading scientists and a total of about 110 academic staff.  Led by Prof Fredrik Karpe, work in OCDEM spans the spectrum of basic, translational and on to patient-orientated research. We are closely integrated with excellent clinical care for patients with diabetes, metabolic and endocrine conditions.

Our particular areas of strength are:

  • Type 2 diabetes including genomics, islet biology and function, novel therapeutics and large-scale clinical trials providing evidence for best practise
  • Human integrative metabolic physiology
  • Endocrine disorders such as glucocorticoid action, pituitary tumours and calcium homeostasis

Our major funders include AstraZeneca, the European Commission, the Medical Research Council, Merck & Co and the Wellcome Trust

Our Research

Learn more about research taking place in OCDEM.