Contact information
+44 (0)1865 572846
Fax +44 (0)1865 740449
Laura Bourne
laura.bourne@cardiov.ox.ac.uk
Research groups
Colleges
Websites
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Cardiovascular Clinical Research Facility
Clinical facility
- Paul Leeson
DPhil Supervisor Profile
Paul Leeson
PhD FRCP FESC
Professor of Cardiovascular Medicine
- Head of Oxford Cardiovascular Clinical Research Facility
- Consultant Physician
Cardiovascular Imaging and Early Development of Cardiovascular Disease
Paul Leeson is Professor of Cardiovascular Medicine at the University of Oxford, Fellow at Wolfson College and Head of the Oxford Cardiovascular Clinical Research Facility. He is also a Consultant Cardiologist at the John Radcliffe Hospital, where he provides expertise in Cardiovascular Imaging, as well as General Cardiology and Cardiovascular Prevention through the Oxford Specialist Hypertension Clinic.
He heads the Preventive Cardiology Research Group, based in the Oxford Cardiovascular Clinical Research Facility, which aims to improve how we identify and prevent heart disease in young people. The group works in three areas:
- Novel markers of early disease - Using imaging and laboratory studies to identify early cardiac and vascular changes in young people at risk of cardiovascular disease. In particular, those predisposed to hypertension, such as families with a history of preeclampsia or preterm birth.
- Young adult cardiovascular prevention trials - Running trials to understand how novel approaches to lifestyle and clinical management can modify early risk cardiovascular phenotypes to prevent the development of later disease.
- Artificial intelligence - Pioneering use of artificial intelligence to improve the clinical tools already available to identify those at risk, such as stress echocardiography, and identify next generation imaging and management approaches.
He sits on the NIHR Invention for Innovation funding panel and UK Biobank Imaging Advisory Board. In addition, he is a National Cardiology Lead for the NIHR Clinical Research Network and member of research collaborative working groups within the European Association of Preventive Cardiology, British Cardiovascular Society and British and Irish Hypertension Society.
Key publications
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Journal article
Upton R. et al, (2021), JACC Cardiovasc Imaging
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Journal article
Hanssen H. et al, (2021), European Journal of Preventive Cardiology
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Journal article
Corral-Acero J. et al, (2020), Eur Heart J, 41, 4556 - 4564
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Journal article
Williamson W. et al, (2018), JAMA, 320, 665 - 673
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Journal article
Huckstep OJ. et al, (2018), J Am Coll Cardiol, 71, 1347 - 1356
Recent publications
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Effect of Self-monitoring of Blood Pressure on Blood Pressure Control in Pregnant Individuals With Chronic or Gestational Hypertension: The BUMP 2 Randomized Clinical Trial.
Journal article
Chappell LC. et al, (2022), JAMA, 327, 1666 - 1678
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Effect of Self-monitoring of Blood Pressure on Diagnosis of Hypertension During Higher-Risk Pregnancy: The BUMP 1 Randomized Clinical Trial.
Journal article
Tucker KL. et al, (2022), JAMA, 327, 1656 - 1665
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Effect of Moderate to High Intensity Aerobic Exercise on Blood Pressure in Young Adults: The TEPHRA open, two-arm, parallel superiority randomized clinical trial
Journal article
LEESON C., (2022), EClinicalMedicine
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Postpartum blood pressure self-management following hypertensive pregnancy: protocol of the Physician Optimised Post-partum Hypertension Treatment (POP-HT) trial.
Journal article
Kitt J. et al, (2022), BMJ Open, 12
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Myocardial work and left ventricular mechanical adaptations following isometric exercise training in hypertensive patients.
Journal article
O'Driscoll JM. et al, (2022), Eur J Appl Physiol
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Automated Echocardiographic Detection of Severe Coronary Artery Disease Using Artificial Intelligence.
Journal article
Upton R. et al, (2021), JACC Cardiovasc Imaging