Research in the Investigative Medicine Division
Buchan Group: Laboratory of Cerebral Ischemia
Investigative Medicine Division
The Laboratory of Cerebral Ischemia is a pre-clinical research group aiming to discover both the mechanisms which underlie cell death in stroke and to develop novel strategies to reduce this.
Buchan Group: Responsible Research and Innovation
Investigative Medicine Division
We are focusing on how to make research and innovation relevant to society, sustainable and fair for everyone.
Davis Group: T-cell Biology
Investigative Medicine Division MRC Human Immunology Unit MRC Weatherall Institute of Molecular Medicine
We are interested in how lymphocytes decide to mount immune responses against, for example, tumours. This involves trying to understanding how leukocyte receptors, such as the T-cell receptor and immune checkpoints, are triggered.
Drakesmith Group: Iron and Immunity
Investigative Medicine Division MRC Human Immunology Unit MRC Weatherall Institute of Molecular Medicine
We are investigating how iron and anaemia influence immunity and infectious diseases. Our research inspires treatments that control iron physiology to benefit the host at the expense of pathogens.
Dong Group: Human T cell responses against Viruses & Cancer
Investigative Medicine Division MRC Human Immunology Unit MRC Weatherall Institute of Molecular Medicine
Our group focuses on determining the factors which affect T cells both in the control of viral infection and in the development of cancer.
Eggeling Group
Investigative Medicine Division MRC Human Immunology Unit MRC Weatherall Institute of Molecular Medicine
We apply and optimize advanced optical microscopy techniques, such as super-resolution STED microscopy, to decipher molecular dynamics in an unprecedented way. Our main focus is molecular plasma membrane organization, especially following immune responses.
Jackson Group: Lymphatic Trafficking Research Group
Investigative Medicine Division MRC Human Immunology Unit MRC Weatherall Institute of Molecular Medicine
We focus on the mechanisms controlling the migration of leucocytes and tumour cells via lymph in health and disease.
Ogg Group: Cutaneous Immunology Group
Investigative Medicine Division MRC Human Immunology Unit MRC Weatherall Institute of Molecular Medicine
The aim of the group is to understand, at the molecular and cellular level, the role of human cutaneous immune responses in mechanisms of disease, treatment and vaccination. As well as contributing to an understanding of disease pathogenesis, we aim to translate our findings to changes in clinical practice.
Rehwinkel Group: Nucleic Acid Sensing
Investigative Medicine Division MRC Human Immunology Unit MRC Weatherall Institute of Molecular Medicine
Simmons Group: Intestinal Immunity in Health and Disease
MRC Human Immunology Unit MRC Weatherall Institute of Molecular Medicine
We define how the immune system functions in the intestine to promote health. We uncover the immune pathogenesis of intestinal diseases such as inflammatory bowel disease to develop better ways to treat these disorders.
Koohy Group: Machine Learning and Integrative Approaches in Immunology
Investigative Medicine Division MRC Human Immunology Unit MRC Weatherall Institute of Molecular Medicine
We would like to understand the functional and molecular mechanisms of the immune system in various immunologically important conditions such as cancer, infection, autoimmune disease as well as ageing. We have a special interest in computational cancer immunotherapy such as antigen presentation, neo-antigen identification and T cell recognition of neo-antigens as well as interrogating the immune response to personalized vaccines from neo-antigens.
Kusumbe Lab | Tissue and Tumor Microenvironments
Investigative Medicine Division MRC Human Immunology Unit
Understanding Vascular Changes & Vascular Diversity Over Time To Treat Diseases