Hospital red blood cell and platelet supply and utilization from March to December of the first year of the COVID-19 pandemic: The BEST Collaborative Study.
Lu W., Yazer M., Li N., Ziman A., Wendel S., Tang H., Tsang H., Titlestad K., Thibodeaux SR., Shih AW., Poisson JL., Pham T., Pandey S., Pagano MB., Shan H., Murphy M., Murphy C., Savioli ML., Kutner JM., Hess AS., Fontaine MJ., Fachini R., Dunbar NM., Kaufman RM., Biomedical Excellence for Safer Transfusions Collaborative None.
BACKGROUND: At the start of the COVID-19 pandemic, widespread blood shortages were anticipated. We sought to determine how hospital blood supply and blood utilization were affected by the first wave of COVID-19. STUDY DESIGN AND METHODS: Weekly red blood cell (RBC) and platelet (PLT) inventory, transfusion, and outdate data were collected from 13 institutions in the United States, Brazil, Canada, and Denmark from March 1st to December 31st of 2020 and 2019. Data from the sites were aligned based on each site's local 1st peak of COVID-19 cases, and data from 2020 (pandemic year) were compared with data from the corresponding period in 2019 (pre-pandemic baseline). RESULTS: RBC inventories were 3% lower in 2020 than in 2019 (680 v. 704, p <0.001) and 5% fewer RBCs were transfused per week compared to 2019 (477 v. 501, p <0.001). However, during the 1st COVID-19 peak, RBC and PLT inventories were higher than normal, as reflected by deviation from par, days on hand, and percent outdated. At this time, 16% fewer inpatient beds were occupied, and 43% fewer surgeries were performed compared to 2019 (p <0.001). In contrast to 2019 when there was no correlation, there was, in 2020, significant negative correlations between RBC and PLT days on hand and both percentage occupancy of inpatient beds and percentage of surgeries performed. CONCLUSION: During the COVID-19 pandemic in 2020, RBC and PLT inventories remained adequate. During the first wave of cases, significant decreases in patient care activities were associated with excess RBC and PLT supplies and increased product outdating.