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We analysed factors associated with neutralising antibody levels in 330 convalescent plasma donors. Women and younger donors were more likely not to have measurable neutralising antibodies, while higher antibody levels were observed in men, in older donors and in those who had been hospitalised. These data will be of value in the timely recruitment of convalescent plasma donors most likely to have high levels of neutralising antibodies for ongoing studies investigating its effectiveness.

Original publication

DOI

10.2807/1560-7917.ES.2020.25.45.2001754

Type

Journal article

Journal

Euro Surveill

Publication Date

11/2020

Volume

25

Keywords

COVID-19, SARS-CoV-2, convalescent plasma, multivariable model, neutralising antibody levels, plasma donor, Age Factors, Aged, Antibodies, Neutralizing, Antibodies, Viral, Betacoronavirus, Blood Donors, Coronavirus Infections, England, Enzyme-Linked Immunosorbent Assay, Hospitalization, Humans, Immunization, Passive, Male, Pandemics, Pneumonia, Viral, Sex Factors