NOVO NORDISK POSTDOCTORAL RESEARCH FELLOW
I graduated from the University of Florida with a dual BS/BA in Microbiology and Anthropology. Subsequently, I completed my PhD in Molecular Biology and Physiology at the University of Alabama, Birmingham, as part of the prestigious Comprehensive Diabetes Research Center. Under the supervision of Dr Chad Hunter, I investigated various aspects of brown adipose biology. In particular, my research illuminated novel transcriptional co-regulators governing tissue function and applications of brown adipose as an islet transplantation site.
Starting in November 2021, I will begin as a Novo Nordisk Postdoctoral Research Fellow in the lab of Dr Katherine Bull and Professor Richard Cornell (NDM) and Dr Ramneek Gupta (NNRCO). The focus of my research is to identify early modulators of kidney disease in human renal transplant tissue. To complete this project, I will develop and utilize integrated imaging ‘omics’ platforms that can be applied to renal biopsies to reveal causative pathways and possible drug targets.
LDB1-mediated transcriptional complexes are sensitive to islet stress.
Liu Y. et al, (2022), Islets, 14, 58 - 68
The transcriptional co-regulator LDB1 is required for brown adipose function.
Kepple JD. et al, (2021), Mol Metab, 53
Xenotransplantation of tannic acid-encapsulated neonatal porcine islets decreases proinflammatory innate immune responses.
Barra JM. et al, (2021), Xenotransplantation
ATM is required for SOD2 expression and homeostasis within the mammary gland.
Dyer LM. et al, (2017), Breast Cancer Res Treat, 166, 725 - 741