Contact information
DPHIL SUPERVISOR PROFILE
Gillian Douglas
PhD
University Research Lecturer
Large studies linking common variations to the occurrence of coronary artery disease have enabled us to identify several new genes that may have a causative influence on the susceptibility to developing coronary artery disease. However, for many of these genes the mechanism by which they alter cardiovascular disease pathology is unknown.
Recent publications
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Nox2 contributes to age-related oxidative damage to neurons and the cerebral vasculature.
Journal article
Fan LM. et al, (2019), J Clin Invest, 130
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LOSS OF KIAA1462, A CORONARY ARTERY DISEASE ASSOCIATED GENE, DECREASES ATHEROSCLEROSIS
Conference paper
Douglas G. et al, (2018), CARDIOVASCULAR RESEARCH, 114, S3 - S3
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Effect of irradiation and bone marrow transplantation on angiotensin II-induced aortic inflammation in ApoE knockout mice.
Journal article
Patel J. et al, (2018), Atherosclerosis, 276, 74 - 82
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Vascular wall regulator of G-protein signalling-1 (RGS-1) is required for angiotensin II-mediated blood pressure control.
Journal article
Patel J. et al, (2018), Vascul Pharmacol, 108, 15 - 22
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JCAD, a Gene at the 10p11 Coronary Artery Disease Locus, Regulates Hippo Signaling in Endothelial Cells.
Journal article
Jones PD. et al, (2018), Arterioscler Thromb Vasc Biol, 38, 1711 - 1722