University Research Lecturer
Large studies linking common variations to the occurrence of coronary artery disease have enabled us to identify several new genes that may have a causative influence on the susceptibility to developing coronary artery disease. However, for many of these genes the mechanism by which they alter cardiovascular disease pathology is unknown.
Roles for endothelial cell and macrophage Gch1 and tetrahydrobiopterin in atherosclerosis progression.
Douglas G. et al, (2018), Cardiovasc res, 114, 1385 - 1399
Endothelial Cell Tetrahydrobiopterin Modulates Sensitivity to Ang (Angiotensin) II-Induced Vascular Remodeling, Blood Pressure, and Abdominal Aortic Aneurysm.
Chuaiphichai S. et al, (2018), Hypertension, 72, 128 - 138
THE CORONARY ARTERY DISEASE ASSOCIATED GENE JCAD REGULATES HIPPO SIGNALLING IN ENDOTHELIAL CELLS
Jones PD. et al, (2018), Heart, 104, A71 - A71
JCAD Gene at the 10p11 Coronary Artery Disease Locus Regulates Hippo Signaling in Endothelial Cells.
Jones PD. et al, (2018), Arterioscler thromb vasc biol
Vascular wall regulator of G-protein signalling-1 (RGS-1) is required for angiotensin II-mediated blood pressure control.
Patel J. et al, (2018), Vascul pharmacol