University Research Lecturer
Large studies linking common variations to the occurrence of coronary artery disease have enabled us to identify several new genes that may have a causative influence on the susceptibility to developing coronary artery disease. However, for many of these genes the mechanism by which they alter cardiovascular disease pathology is unknown.
Endothelial Cell Tetrahydrobiopterin Modulates Sensitivity to Ang (Angiotensin) II-Induced Vascular Remodeling, Blood Pressure, and Abdominal Aortic Aneurysm.
Chuaiphichai S. et al, (2018), Hypertension
Vascular wall regulator of G-protein signalling-1 (RGS-1) is required for angiotensin II-mediated blood pressure control.
Patel J. et al, (2018), Vascul Pharmacol
A new role for RGS-1 in vascular function and blood pressure regulation
Patel J. et al, (2018), CARDIOVASCULAR RESEARCH, 114, S88 - S88
Deficiency in endothelial cell tetrahydrobiopterin increases resistance vascular remodelling, blood pressure, and susceptibility to aortic abdominal aneurysm in response to angiotensin II
Chuaiphichai S. et al, (2018), CARDIOVASCULAR RESEARCH, 114, S90 - S90
Roles for Endothelial Cell and Macrophage Gch1 and Tetrahydrobiopterin in Atherosclerosis Progression.
Douglas G. et al, (2018), Cardiovasc Res