Alison Simmons
Research groups
Alison Simmons
PhD FRCP FMedSci
Director of the MRC Translational Immune Discovery Unit
- Consultant Physician
- Professor of Gastroenterology
Key publications
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Tracking in situ checkpoint inhibitor-bound target T cells in patients with checkpoint-induced colitis.
Journal article
Gupta T. et al, (2024), Cancer Cell, 42, 797 - 814.e15
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Spatiotemporal analysis of human intestinal development at single-cell resolution.
Journal article
Fawkner-Corbett D. et al, (2021), Cell, 184, 810 - 826.e23
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Single-cell atlas of colonic CD8+ T cells in ulcerative colitis.
Journal article
Corridoni D. et al, (2020), Nat Med, 26, 1480 - 1490
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Colonic epithelial cell diversity in health and inflammatory bowel disease.
Journal article
Parikh K. et al, (2019), Nature, 567, 49 - 55
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Invasive Salmonella exploits divergent immune evasion strategies in infected and bystander dendritic cell subsets.
Journal article
Aulicino A. et al, (2018), Nat Commun, 9
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Structural Remodeling of the Human Colonic Mesenchyme in Inflammatory Bowel Disease.
Journal article
Kinchen J. et al, (2018), Cell, 175, 372 - 386.e17
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Snapin promotes HIV-1 transmission from dendritic cells by dampening TLR8 signaling.
Journal article
Khatamzas E. et al, (2017), EMBO J, 36, 2998 - 3011
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The intracellular sensor NOD2 induces microRNA-29 expression in human dendritic cells to limit IL-23 release.
Journal article
Brain O. et al, (2013), Immunity, 39, 521 - 536
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NOD2 stimulation induces autophagy in dendritic cells influencing bacterial handling and antigen presentation.
Journal article
Cooney R. et al, (2010), Nat Med, 16, 90 - 97