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Siyu Chen
DPhil Student
I’m a DPhil student in Professor David Ray’s group, co-supervised by Dr Jelena Bezbradica Mirkovic, Professor David Hodson, and Dr Nick Ciccone.
My DPhil research focuses on the circadian regulation of macrophage immune response and metabolism in health and chronic inflammatory diseases. Using a combination of experimental and computational approaches, I’m working to understand how macrophages align their daily activities with the optimal time and tissue environment.
Prior to this, I completed my BSc degree in Biological Sciences at Sun Yat-sen University in China with an Outstanding Graduates award, and my MSc degree in Integrated Immunology at the University of Oxford.
Beyond my DPhil studies, I’m passionate about science communication. By infusing science with the art of illustration and the craft of writing, I’m hoping to make it more accessible and meaningful in people’s lives.
Publications
Comprehensive detrimental effects of a simulated frequently shifting schedule on diurnal rhythms and vigilance. Ma, X. et al. Chronobiology International 39, 1-12, doi:10.1080/07420528.2022.2101371 (2022).
A Population-Level Analysis of Changes in Circadian Rhythms and Sleep and Their Association with Negative Emotions during the Outbreak of COVID-19 in China. Chen, S. et al. COVID 2, 450-463, doi:10.3390/covid2040032 (2022).
Circadian misalignment leads to changes in cortisol rhythms, blood biochemical variables and serum miRNA profiles. Huang, G. et al. Biochemical and biophysical research communications 567, 9-16, doi:10.1016/j.bbrc.2021.06.015 (2021).