CalTrack: High-Throughput Automated Calcium Transient Analysis in Cardiomyocytes.

Psaras Y.; Margara F.; Cicconet M.; Sparrow AJ.; Repetti GG.; Schmid M.; Steeples V.; Wilcox JAL.; Bueno-Orovio A.; Redwood CS.; Watkins HC.; Robinson P.; Rodriguez B.; Seidman JG.; Seidman CE.; Toepfer CN.

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CalTrack: High-Throughput Automated Calcium Transient Analysis in Cardiomyocytes.

Psaras Y., Margara F., Cicconet M., Sparrow AJ., Repetti GG., Schmid M., Steeples V., Wilcox JAL., Bueno-Orovio A., Redwood CS., Watkins HC., Robinson P., Rodriguez B., Seidman JG., Seidman CE., Toepfer CN.

[Figure: see text].

Original publication

DOI

10.1161/CIRCRESAHA.121.318868

Type

Journal article

Journal

Circ Res

Publication Date

09/07/2021

Volume

129

Pages

326 - 341

Keywords

calcium, cardiomyopathy, hypertrophic, induced pluripotent stem cells, myocytes, cardiac, photobleaching, Algorithms, Animals, Automation, Laboratory, Calcium, Calcium Signaling, Cells, Cultured, Guinea Pigs, High-Throughput Screening Assays, Humans, Image Processing, Computer-Assisted, Induced Pluripotent Stem Cells, Kinetics, Microscopy, Fluorescence, Mutation, Missense, Myocytes, Cardiac, Troponin I, Workflow