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RDM Principal Investigators have been the founders, or co-founders, of 18 spinout companies since 2010. This is one of the main ways in which we turn research discoveries into innovations that generate impact, and ultimately clinical benefit for patients.

Close-up of hand working at lab bench
Company Name Description RDM PI Year
Thelior Bio Target discovery via spatial transcriptomics Alison Simmons 2025
Yellowstone Biosciences Soluble T-cell receptor (TCR)-based therapies Paresh Vyas 2024
Eterna Biologics RNA-targeting medicines Tatjana Sauka Spengler 2024
Ramanomics (now Vivid Dx) New technologies for antimicrobial resistance Monique Andersson 2024
Alveogene Lentiviral-based gene therapies for respiratory diseases Deborah Gill and Steve Hyde 2023
IngenOx Delivery of precision medicine drugs and vaccines for cancer treatment David Kerr 2023
Alethiomics (now Alethio Therapeutics) New methodologies for single cell genomics Adam Mead and Bethan Psaila 2023
T-Cypher Bio T cell receptor based therapeutics for immune-mediated disease Graham Ogg 2021
Dark Blue Therapeutics Research and experimental development on biotechnology Thomas Milne 2020
Singula Bio Developing novel neoantigen-based cell therapies for patients with solid tumours Vincenzo Cerundolo 2020
Nucleome Therapeutics Platform technology based on NG capture-c technique computational pipelines Jim Hughes and James Davies 2019
MiroBio (sold) Treating a range of autoimmune and inflammatory disorders Simon Davis 2019
Caristo Diagnostics Novel biomarkers to detect inflammation and risk in coronary heart disease Charis Antoniades, Keith Channon and Stefan Neubauer 2018
Ultromics Echo Machine Learning Assay Paul Leeson 2017
Orbit Discovery Identifying peptide drugs for a range of chronic diseases Graham Ogg 2015
iOx Therapeutics (sold) Developing a novel cancer immunotherapy Vincenzo Cerundolo 2015
Perspectum Diagnostics Developing solutions for major unmet needs in diagnostic medicine in multiple internal organs Stefan Neubauer 2013
Oxford Cancer Biomarkers Identifying novel genetic SNPs in patients at risk of life-threatening side effects David Kerr 2010