Cookies on this website

We use cookies to ensure that we give you the best experience on our website. If you click 'Accept all cookies' we'll assume that you are happy to receive all cookies and you won't see this message again. If you click 'Reject all non-essential cookies' only necessary cookies providing core functionality such as security, network management, and accessibility will be enabled. Click 'Find out more' for information on how to change your cookie settings.

Accept all cookies Reject all non-essential cookies Find out more

Contact information


bethan.psaila@ndcls.ox.ac.uk

Colleges

Collaborators

Bethan Psaila

MA; MBBS; MRCP; FRCPath; PhD

Associate Professor of Haematology

  • Cancer Research UK Advanced Clinician Scientist

Using single-cell approaches to study normal and malignant megakaryocyte development and myeloproliferative neoplasms

I study megakaryocytes - large, rare cells found in the bone marrow that release blood platelets into the circulation and also produce many growth factors and other proteins that regulate blood cell development and the bone marrow microenvironment. My group applies state-of-the-art single-cell approaches to clarify the cellular pathways by which megakaryocytes arise from haematopoietic stem cells. This is important as in certain malignancies, such as erythro-megakaryocytic leukaemias and myeloproliferative neoplasms, megakaryocytes develop abnormally and contribute to key pathological features of the disease, including the harmful scarring that destroys the bone marrow.

I trained at Clare College, Cambridge, Imperial College London/The Hammersmith Hospital, Cornell, New York, and the National Institutes of Health, Bethesda USA and am currently a Cancer Research UK Advanced Clinician Scientist and Honorary Consultant in Haematology, Oxford University Hospitals NHS Trust. I am also a Senior Fellow of New College, Oxford. 

Social media

Key publications

Recent publications

More publications

ORCID

0000-0001-8198-9663