Research groups
Colleges
Websites
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Paul Leeson
Web profile
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Cardiovascular DIsease and Pregnancy Research Collaborative
Research Collaboration
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National Echocardiography Research Network
Research Collaboration
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Cardiovascular Clinical Research Facility
Clinical facility
Paul Leeson
PhD FRCP FESC
Professor of Cardiovascular Medicine
- Head of Oxford Cardiovascular Clinical Research Facility
- Consultant Physician
Cardiovascular Imaging and Early Development of Cardiovascular Disease
Paul Leeson is Professor of Cardiovascular Medicine at the University of Oxford, Fellow at Wolfson College and Head of the Oxford Cardiovascular Clinical Research Facility. He is also a Consultant Cardiologist at the John Radcliffe Hospital, where he provides expertise in Cardiovascular Imaging, as well as General Cardiology and Cardiovascular Prevention through the Oxford Specialist Hypertension Clinic.
He heads the Preventive Cardiology Research Group, based in the Oxford Cardiovascular Clinical Research Facility, which aims to improve how we identify and prevent heart disease in young people. The group works in three areas:
- Novel markers of early disease - Using imaging and laboratory studies to identify early cardiac and vascular changes in young people at risk of cardiovascular disease. In particular, those predisposed to hypertension, such as families with a history of preeclampsia or preterm birth.
- Young adult cardiovascular prevention trials - Running trials to understand how novel approaches to lifestyle and clinical management can modify early risk cardiovascular phenotypes to prevent the development of later disease.
- Artificial intelligence - Pioneering use of artificial intelligence to improve the clinical tools already available to identify those at risk, such as echocardiography, and identify next generation imaging and management approaches.
He sits on the NIHR i4i and Fellowship funding panels, NICE Cardiovascular Disease Prevention Guideline committee and UK Biobank Imaging Advisory Board. In addition, he is a National Cardiology Lead for the NIHR Clinical Research Network and leads research collaborative working groups within both imaging and cardiovascular prevention.
Key publications
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Journal article
Kitt J. et al, (2023), JAMA, 330, 1991 - 1999
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Journal article
de Simone G. et al, (2022), Eur Heart J
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Journal article
Hanssen H. et al, (2021), European Journal of Preventive Cardiology
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Journal article
Upton R. et al, (2021), JACC Cardiovasc Imaging
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Journal article
Williamson W. et al, (2018), JAMA, 320, 665 - 673
Recent publications
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Long-Term outcomes after stress echocardiography in real world practice: five-year follow-up of the UK Evarest study.
Journal article
Woodward W. et al, (2024), Eur Heart J Cardiovasc Imaging
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Author Response to Discussion Forum - EVAREST trial by Max Berrill.
Journal article
Woodward W. and Leeson P., (2024), Eur Heart J Cardiovasc Imaging
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Novel Role of 5-Methyl-(6S)-Tetrahydrofolate in Mediating Endothelial Cell Tetrahydrobiopterin in Pregnancy and Implications for Gestational Hypertension.
Journal article
Dickinson Y. et al, (2024), Hypertension
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Are We Ready to Let AI Replace the Human "Eye" When Looking for Wall Motion Abnormalities?
Journal article
Johnson CL. and Leeson P., (2024), J Am Soc Echocardiogr, 37, 664 - 665
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Isometric Exercise Training and Arterial Hypertension: An Updated Review.
Journal article
Edwards JJ. et al, (2024), Sports Med
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Left Atrial Mechanics Following Preeclamptic Pregnancy.
Journal article
O'Driscoll JM. et al, (2024), Hypertension