Research groups
Research Projects Available
Colleges
Websites
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Paul Leeson
Web profile
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Cardiovascular DIsease and Pregnancy Research Collaborative
Research Collaboration
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National Echocardiography Research Network
Research Collaboration
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Cardiovascular Clinical Research Facility
Clinical facility
Paul Leeson
PhD FRCP FESC
Professor of Cardiovascular Medicine
- Academic Lead for Innovation, Medical Sciences Division
- Head of Oxford Cardiovascular Clinical Research Facility
- Consultant Cardiologist, Oxford University Hospitals
Cardiovascular Imaging and Early Development of Cardiovascular Disease
Paul Leeson is Professor of Cardiovascular Medicine at the University of Oxford, Fellow at Wolfson College and the Academic Lead for Innovation within the Medical Sciences Division.
He is also a Consultant Cardiologist at the John Radcliffe Hospital, where he provides expertise in Cardiovascular Imaging, as well as General Cardiology and Cardiovascular Prevention, through the Oxford Specialist Hypertension Clinic.
He heads the Preventive Cardiology Research Group, based in the Oxford Cardiovascular Clinical Research Facility, which aims to improve how we identify and prevent heart disease in young people. The group works in three areas:
- Novel markers of early disease - Using imaging and laboratory studies to identify early cardiac and vascular changes in young people at risk of cardiovascular disease. In particular, those predisposed to hypertension, such as families with a history of preeclampsia or preterm birth.
- Young adult cardiovascular prevention trials - Running trials to understand how novel approaches to lifestyle and clinical management can modify early risk cardiovascular phenotypes to prevent the development of later disease.
- Artificial intelligence - Pioneering use of artificial intelligence within preventive cardiology and imaging to better identify and manage those at risk; with innovations now having been patented, spun out from the group, and turned into medical devices.
He chairs a NIHR i4i Product Development Awards funding panel, as well as sitting on the UK Biobank Imaging Advisory Board and NIHR Doctoral Fellowship Committee. He has a broad experience within innovation and preventive cardiology having previously been a National Cardiology Lead for the NIHR Clinical Research Network and chair of the European Association of Preventive Cardiology research nucleus, as well as a past member of the NICE Cardiovascular Disease Prevention Guideline committee and several European Society of Cardiology position statement writing groups,
Key publications
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Long-Term Blood Pressure Control After Hypertensive Pregnancy Following Physician-Optimized Self-Management: The POP-HT Randomized Clinical Trial.
Journal article
Kitt J. et al, (2023), JAMA, 330, 1991 - 1999
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Hypertension in children and adolescents.
Journal article
de Simone G. et al, (2022), Eur Heart J
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Personalized exercise prescription in the prevention and treatment of arterial hypertension: a Consensus Document from the European Association of Preventive Cardiology (EAPC) and the ESC Council on Hypertension
Journal article
Hanssen H. et al, (2021), European Journal of Preventive Cardiology
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Automated Echocardiographic Detection of Severe Coronary Artery Disease Using Artificial Intelligence.
Journal article
Upton R. et al, (2021), JACC Cardiovasc Imaging
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Association of Cardiovascular Risk Factors With MRI Indices of Cerebrovascular Structure and Function and White Matter Hyperintensities in Young Adults.
Journal article
Williamson W. et al, (2018), JAMA, 320, 665 - 673
Recent publications
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Subclinical Postpartum Renal Structure After Hypertensive Pregnancy Disorders.
Journal article
Cutler HR. et al, (2025), Hypertension
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Clinical research and trials in echocardiography: rationale, requirements and future opportunities.
Journal article
Johnson CL. et al, (2025), Echo Res Pract, 12
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Systematic review and meta-analysis of the importance of pre-pregnancy maternal health on the risk of hypertensive disorders of pregnancy.
Journal article
Rodriguez-Caro H. et al, (2025), Pregnancy Hypertens, 41
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International guidelines for the management of hypertensive disorders of pregnancy: an opportunity to improve the lifelong health of women?
Journal article
Frost A. et al, (2025), Eur J Prev Cardiol
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Evaluating the J-wave as a Marker of Diastolic Dysfunction in Heart Failure with Preserved Ejection Fraction.
Journal article
Alwani T. et al, (2025), J Am Soc Echocardiogr
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Exercise Improves Myocardial Deformation But Not Cardiac Structure in Preterm-Born Adults: A Randomized Clinical Trial.
Journal article
Lapidaire W. et al, (2025), JACC Adv, 4
