Research groups
Research Projects Available
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Paul Leeson
Web profile
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Medical Sciences Division Innovation
Role
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Cardiovascular Clinical Research Facility
Clinical facility
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Cardiovascular DIsease and Pregnancy Research Collaborative
Research Collaboration
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National Echocardiography Research Network
Research Collaboration
Paul Leeson
PhD FRCP FESC
Professor of Cardiovascular Medicine
- Academic Lead for Innovation, Medical Sciences Division
- Head of Oxford Cardiovascular Clinical Research Facility
- Consultant Cardiologist, Oxford University Hospitals
Cardiovascular Imaging and Early Development of Cardiovascular Disease
Paul Leeson is Professor of Cardiovascular Medicine at the University of Oxford, Fellow at Wolfson College and the Academic Lead for Innovation within the Medical Sciences Division.
He is also a Consultant Cardiologist at the John Radcliffe Hospital, where he provides expertise in Cardiovascular Imaging, as well as General Cardiology and Cardiovascular Prevention, through the Oxford Specialist Hypertension Clinic.
He heads the Preventive Cardiology Research Group, based in the Oxford Cardiovascular Clinical Research Facility, which aims to improve how we identify and prevent heart disease in young people. The group works in three areas:
- Novel markers of early disease - Using imaging and laboratory studies to identify early cardiac and vascular changes in young people at risk of cardiovascular disease. In particular, those predisposed to hypertension, such as families with a history of preeclampsia or preterm birth.
- Young adult cardiovascular prevention trials - Running trials to understand how novel approaches to lifestyle and clinical management can modify early risk cardiovascular phenotypes to prevent the development of later disease.
- Artificial intelligence - Pioneering use of artificial intelligence within preventive cardiology and imaging to better identify and manage those at risk; with innovations now having been patented, spun out from the group, and turned into medical devices.
He chairs a NIHR i4i Product Development Awards funding panel, as well as sitting on the UK Biobank Imaging Advisory Board and NIHR Doctoral Fellowship Committee. He has a broad experience within innovation and preventive cardiology having previously been a National Cardiology Lead for the NIHR Clinical Research Network and chair of the European Association of Preventive Cardiology research nucleus, as well as a past member of the NICE Cardiovascular Disease Prevention Guideline committee and several European Society of Cardiology position statement writing groups,
Key publications
Long-Term Blood Pressure Control After Hypertensive Pregnancy Following Physician-Optimized Self-Management: The POP-HT Randomized Clinical Trial.
Journal article
Kitt J. et al, (2023), JAMA, 330, 1991 - 1999
Hypertension in children and adolescents.
Journal article
de Simone G. et al, (2022), Eur Heart J, 43, 3290 - 3301
mated Echocardiographic Detection of Severe Coronary Artery Disease Using Artificial Intelligence.
Journal article
Upton R. et al, (2022), JACC Cardiovasc Imaging, 15, 715 - 727
Personalized exercise prescription in the prevention and treatment of arterial hypertension: a Consensus Document from the European Association of Preventive Cardiology (EAPC) and the ESC Council on Hypertension.
Journal article
Hanssen H. et al, (2022), Eur J Prev Cardiol, 29, 205 - 215
ssociation of Cardiovascular Risk Factors With MRI Indices of Cerebrovascular Structure and Function and White Matter Hyperintensities in Young Adults.
Journal article
Williamson W. et al, (2018), JAMA, 320, 665 - 673
Recent publications
n interpretable and explainable neural network to classify sports-related cardiac arrhythmias in professional football athletes
Preprint
Vanegas Mueller E. et al, (2026)
Technical Aspects and Clinical Relevance of Cuffless Devices for Blood Pressure Measurement. A Scientific Statement of the ESC Working Group on e-Cardiology, the ESC Council on Hypertension, and the European Association of Preventive Cardiology of the ESC.
Journal article
Parati G. et al, (2026), Eur J Prev Cardiol
Cardiovascular disease in women: do we focus on single jigsaw pieces or look at the whole puzzle?
Journal article
Krasner S. et al, (2026), Eur J Prev Cardiol, 33, 391 - 393
Cardiac dysfunction during adverse maternal outcomes in hypertensive disorders of pregnancy.
Journal article
Giorgione V. et al, (2026), Acta Obstet Gynecol Scand, 105, 280 - 287
Brain Volumes After Hypertensive Pregnancy and Postpartum Blood Pressure Management: A POP-HT Randomized Clinical Trial Imaging Substudy.
Journal article
Lapidaire W. et al, (2026), JAMA Neurol, 83, 137 - 144
Optimising the monitoring and management of raised blood pressure including proteinuria testing during pregnancy: the BUMP research programme including 2 RCTs
Journal article
McManus RJ. et al, (2026)
