Cookies on this website

We use cookies to ensure that we give you the best experience on our website. If you click 'Accept all cookies' we'll assume that you are happy to receive all cookies and you won't see this message again. If you click 'Reject all non-essential cookies' only necessary cookies providing core functionality such as security, network management, and accessibility will be enabled. Click 'Find out more' for information on how to change your cookie settings.

Andy Rimmer, Katherine Bull
Description LGENU is a program designed to infer ancestral haplotypes in ENU-mutated mice, from next-generation SNP calls, using the Lander-Green algorithm.
Capabilities The program currently works properly only for a fixed pedigree, and needs SNP data from 3 sibling mice. It takes a VCF file of SNP calls, a map of recombination rates across the mouse genome, a window size, and a value for the ENU mutation rate. The output is a text file consisting of inferred ancestral haplotypes across the genome for each moue. A test VCF file  is provided with the program.
A manuscript describing this method is currently being prepared for publication.
Resources: You can download the latest stable version of LGENU  here.
Contact: Bug reports, comments, and feature requests can be sent to Andy Rimmer