Investigators:
|
Andy Rimmer, Katherine Bull |
| Description |
LGENU is a program designed to infer ancestral haplotypes in ENU-mutated mice, from next-generation SNP calls, using the Lander-Green algorithm. |
| Capabilities |
The program currently works properly only for a fixed pedigree, and needs SNP data from 3 sibling mice. It takes a VCF file of SNP calls, a map of recombination rates across the mouse genome, a window size, and a value for the ENU mutation rate. The output is a text file consisting of inferred ancestral haplotypes across the genome for each moue. A test VCF file is provided with the program. |
Reference:
|
A manuscript describing this method is currently being prepared for publication. |
| Resources: |
You can download the latest stable version of LGENU here. |
| Contact: |
Bug reports, comments, and feature requests can be sent to Andy Rimmer |
