Publications — Radcliffe Department of Medicine

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Proteostasis and resilience in the mechanically-stressed vascular endothelium

Keen A. et al, (2023), Current Opinion in Physiology, 34

Mechanical Forces and Their Effect on the Ribosome and Protein Translation Machinery.

Simpson LJ. et al, (2020), Cells, 9

The guidance receptor plexin D1 is a mechanosensor in endothelial cells.

Mehta V. et al, (2020), Nature, 578, 290 - 295

Mechanical Regulation of Protein Translation in the Cardiovascular System.

Simpson LJ. et al, (2020), Front Cell Dev Biol, 8

Role of aminoacyl tRNA syntheses in infectious diseases

READER J., (2019)

Haemodynamics Regulate Fibronectin Assembly via PECAM.

Chen Z. et al, (2017), Sci Rep, 7

Structural characterization of antibiotic self-immunity tRNA synthetase in plant tumour biocontrol agent

Chopra S. et al, (2016), Nature Communications, 7

A Pyranose-2-Phosphate Motif Is Responsible for Both Antibiotic Import and Quorum-Sensing Regulation in Agrobacterium tumefaciens

El Sahili A. et al, (2015), PLOS Pathogens, 11, e1005071 - e1005071

tRNAs as Antibiotic Targets

Chopra S. and Reader J., (2014), International Journal of Molecular Sciences, 16, 321 - 349

Haemodynamic and extracellular matrix cues regulate the mechanical phenotype and stiffness of aortic endothelial cells.

Collins C. et al, (2014), Nat Commun, 5

Natural aminoacyl tRNA synthetase fragment enhances cardiac function after myocardial infarction.

McCormick ME. et al, (2014), PLoS One, 9

Plant tumour biocontrol agent employs a tRNA-dependent mechanism to inhibit leucyl-tRNA synthetase.

Chopra S. et al, (2013), Nat Commun, 4

The mechanism of microcin C resistance provided by the MccF peptidase.

Tikhonov A. et al, (2010), J Biol Chem, 285, 37944 - 37952

Mammalian aminoacyl-tRNA synthetases: cell signaling functions of the protein translation machinery.

Brown MV. et al, (2010), Vascul Pharmacol, 52, 21 - 26

The novel fragment of tyrosyl tRNA synthetase, mini-TyrRS, is secreted to induce an angiogenic response in endothelial cells.

Greenberg Y. et al, (2008), FASEB J, 22, 1597 - 1605

Erratum: VE-cadherin links tRNA synthetase cytokine to antiangiogenic function (Journal of Biological Chemistry (2005) 280 (2405-2408))

Tzima E. et al, (2007), Journal of Biological Chemistry, 282

VE-cadherin links tRNA synthetase cytokine to antiangiogenic function (vol 280, pg 2405, 2005)

Tzima E. et al, (2007), JOURNAL OF BIOLOGICAL CHEMISTRY, 282, 29068 - 29068

Rhizosphere wars: A tale of three plasmids.

Farrand SK. et al, (2007), PLASMID, 57, 214 - 214

Bases of biocontrol: sequence predicts synthesis and mode of action of agrocin 84, the Trojan horse antibiotic that controls crown gall.

Kim J-G. et al, (2006), Proc Natl Acad Sci U S A, 103, 8846 - 8851

Major biocontrol of plant tumors targets tRNA synthetase.

Reader JS. et al, (2005), Science, 309

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