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31 P-containing metabolites in human blood, serum and erythrocytes were measured or calculated. Phosphodiesters were found in serum, but not in erythrocytes. 2,3-diphosphoglycerate and 2,3-diphosphoglycerate/ATP ratios were increased in patients with congestive heart failure (2,3-diphosphoglycerate by 13% in mild to moderate, 31% in severe congestive heart failure, 2,3-diphosphoglycerate/ATP ratio by 9% in mild to moderate, 38% in severe congestive heart failure); phosphodiesters were increased in diabetes mellitus (by 26%) and even more so in hyperlipidaemia (by 57%). Changes of blood 31 P compounds with disease states may have diagnostic potential and should be recognized for correction of organ spectra. © 1993 Chapman & Hall.

Original publication

DOI

10.1007/BF01760400

Type

Journal article

Journal

MAGMA Magnetic Resonance Materials in Physics, Biology, and Medicine

Publication Date

01/06/1993

Volume

1

Pages

55 - 60