Research groups
Colleges
Websites
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Paul Leeson
Web profile
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Cardiovascular DIsease and Pregnancy Research Collaborative
Research Collaboration
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National Echocardiography Research Network
Research Collaboration
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Cardiovascular Clinical Research Facility
Clinical facility
Paul Leeson
PhD FRCP FESC
Professor of Cardiovascular Medicine
- Head of Oxford Cardiovascular Clinical Research Facility
- Consultant Physician
Cardiovascular Imaging and Early Development of Cardiovascular Disease
Paul Leeson is Professor of Cardiovascular Medicine at the University of Oxford, Fellow at Wolfson College and Head of the Oxford Cardiovascular Clinical Research Facility. He is also a Consultant Cardiologist at the John Radcliffe Hospital, where he provides expertise in Cardiovascular Imaging, as well as General Cardiology and Cardiovascular Prevention through the Oxford Specialist Hypertension Clinic.
He heads the Preventive Cardiology Research Group, based in the Oxford Cardiovascular Clinical Research Facility, which aims to improve how we identify and prevent heart disease in young people. The group works in three areas:
- Novel markers of early disease - Using imaging and laboratory studies to identify early cardiac and vascular changes in young people at risk of cardiovascular disease. In particular, those predisposed to hypertension, such as families with a history of preeclampsia or preterm birth.
- Young adult cardiovascular prevention trials - Running trials to understand how novel approaches to lifestyle and clinical management can modify early risk cardiovascular phenotypes to prevent the development of later disease.
- Artificial intelligence - Pioneering use of artificial intelligence to improve the clinical tools already available to identify those at risk, such as echocardiography, and identify next generation imaging and management approaches.
He sits on the NIHR i4i and Fellowship funding panels, NICE Cardiovascular Disease Prevention Guideline committee and UK Biobank Imaging Advisory Board. In addition, he is a National Cardiology Lead for the NIHR Clinical Research Network and leads research collaborative working groups within both imaging and cardiovascular prevention.
Key publications
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Journal article
Kitt J. et al, (2023), JAMA, 330, 1991 - 1999
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Journal article
de Simone G. et al, (2022), Eur Heart J
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Journal article
Hanssen H. et al, (2021), European Journal of Preventive Cardiology
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Journal article
Upton R. et al, (2021), JACC Cardiovasc Imaging
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Journal article
Williamson W. et al, (2018), JAMA, 320, 665 - 673
Recent publications
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Clinical research and trials in echocardiography: rationale, requirements and future opportunities.
Journal article
Johnson CL. et al, (2025), Echo Res Pract, 12
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Systematic review and meta-analysis of the importance of pre-pregnancy maternal health on the risk of hypertensive disorders of pregnancy.
Journal article
Rodriguez-Caro H. et al, (2025), Pregnancy Hypertens, 41
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International guidelines for the management of hypertensive disorders of pregnancy: an opportunity to improve the lifelong health of women?
Journal article
Frost A. et al, (2025), Eur J Prev Cardiol
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Evaluating the J-wave as a Marker of Diastolic Dysfunction in Heart Failure with Preserved Ejection Fraction.
Journal article
Alwani T. et al, (2025), J Am Soc Echocardiogr
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Exercise Improves Myocardial Deformation But Not Cardiac Structure in Preterm-Born Adults: A Randomized Clinical Trial.
Journal article
Lapidaire W. et al, (2025), JACC Adv, 4
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Author Correction: External validation of artificial intelligence for detection of heart failure with preserved ejection fraction.
Journal article
Akerman AP. et al, (2025), Nat Commun, 16