Oxford Biobank Scientific Coordinator
Matt Neville is the Oxford Biobank and Bioresource Scientific Coordinator, primarily responsible for curation of the Oxford Biobank (OBB) genetic resource and facilitator of Bioresource recruit-by-genotype and recruit-by-phenotype translational research studies available to the Metabolic Research Group (MRG), the larger research community and Industry. Matt's primary research interests focus on understanding the genetic determinants of body fat function and distribution and how this may impact, and be utilised to improve, the health consequences of obesity. Other duties include primary genetic data interrogator and analyst for the MRG, DPhil student supervisor, Lecturer and dissertation supervisor on the Experimental and Translational Therapeutics MSc program and Chair of the senior academic faculty for the OCDEM building.
Matt completed his DPhil in 2000 in human molecular genetics (Ox) followed by 2 years of R&D in industry (TWT, Madison, Wisconsin, US) working on marketable novel genetic assay systems. Previous research has included the contribution of genetics to smoking addiction and cessation within the General Practice Research group (Ox) and collaborations within the Department of Gastroenterology (Ox), imputing extended HLA haplotypes for association studies with autoimmune diseases such as Irritable Bowel Disease and Behçet's disease. In 2003 Matt took on a Postdoctoral Researcher position with Prof Fredrik Karpe investigating the genetics of Adipose tissue function and the adverse consequences of Obesity and Type II Diabetes. As a progression from his previous roles within the MRG and the Oxford Biobank Matt took on the BRC funded position of Oxford Biobank and Bioresource Scientific Coordinator in 2012.
Triglyceride-lowering LPL alleles combined with LDL-C-lowering alleles are associated with an additively improved lipoprotein profile.
Ibi D. et al, (2021), Atherosclerosis
A haemagglutination test for rapid detection of antibodies to SARS-CoV-2.
Townsend A. et al, (2021), Nat Commun, 12
Markers of adipose tissue hypoxia are elevated in subcutaneous adipose tissue of severely obese patients with obesity hypoventilation syndrome but not in the moderately obese.
Todorčević M. et al, (2021), Int J Obes (Lond)
Investigating the relationships between unfavourable habitual sleep and metabolomic traits: evidence from multicohort multivariable regression and Mendelian randomization analyses
CHRISTODOULIDES C., (2021), BMC Medicine
Performance characteristics of five immunoassays for SARS-CoV-2: a head-to-head benchmark comparison.
National SARS-CoV-2 Serology Assay Evaluation Group None., (2020), Lancet Infect Dis, 20, 1390 - 1400