Publications — Radcliffe Department of Medicine

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Genome-wide characterization of circulating metabolic biomarkers.

Karjalainen MK. et al, (2024), Nature

MLX plays a key role in lipid and glucose metabolism in humans: evidence from in vitro and in vivo studies

NAGARAJAN S. et al, (2023), Metabolism: clinical and experimental

Type 2 Diabetes risk alleles in Peptidyl-glycine Alpha-amidating Monooxygenase influence GLP-1 levels and response to GLP-1 Receptor Agonists.

Umapathysivam MM. et al, (2023), medRxiv

Polygenic risk in Type III hyperlipidaemia and risk of cardiovascular disease: An epidemiological study in UK Biobank and Oxford Biobank.

Pieri K. et al, (2022), Int J Cardiol

A saturated map of common genetic variants associated with human height.

Yengo L. et al, (2022), Nature, 610, 704 - 712

High-throughput mass spectrometry maps the sepsis plasma proteome and differences in response

Mi Y. et al, (2022)

A multi-layer functional genomic analysis to understand noncoding genetic variation in lipids.

Ramdas S. et al, (2022), Am J Hum Genet, 109, 1366 - 1387

TCF7L2 plays a complex role in human adipose progenitor biology, which might contribute to genetic susceptibility to type 2 diabetes.

Verma M. et al, (2022), Metabolism, 133

HOTAIR interacts with PRC2 complex regulating the regional preadipocyte transcriptome and human fat distribution.

Kuo F-C. et al, (2022), Cell Rep, 40

The Arg82Cys Polymorphism of the Protein Nepmucin Implies a Role in HDL Metabolism.

Metz S. et al, (2022), J Endocr Soc, 6

Apolipoprotein A-V is a potential target for treating coronary artery disease: evidence from genetic and metabolomic analyses.

Ibi D. et al, (2022), J Lipid Res

The associations between body fat distribution and bone mineral density in the Oxford Biobank: a cross sectional study.

Hilton C. et al, (2021), Expert Rev Endocrinol Metab, 1 - 7

The power of genetic diversity in genome-wide association studies of lipids.

Graham SE. et al, (2021), Nature, 600, 675 - 679

Higher thyrotropin leads to unfavorable lipid profile and somewhat higher cardiovascular disease risk: evidence from multi-cohort Mendelian randomization and metabolomic profiling.

van Vliet NA. et al, (2021), BMC Med, 19

The trans-ancestral genomic architecture of glycemic traits.

Chen J. et al, (2021), Nat Genet, 53, 840 - 860

Triglyceride-lowering LPL alleles combined with LDL-C-lowering alleles are associated with an additively improved lipoprotein profile.

Ibi D. et al, (2021), Atherosclerosis

Publisher Correction: Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals.

Surendran P. et al, (2021), Nat Genet, 53

A haemagglutination test for rapid detection of antibodies to SARS-CoV-2.

Townsend A. et al, (2021), Nat Commun, 12

Markers of adipose tissue hypoxia are elevated in subcutaneous adipose tissue of severely obese patients with obesity hypoventilation syndrome but not in the moderately obese.

Todorčević M. et al, (2021), Int J Obes (Lond)

Investigating the relationships between unfavourable habitual sleep and metabolomic traits: evidence from multicohort multivariable regression and Mendelian randomization analyses

CHRISTODOULIDES C., (2021), BMC Medicine

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