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Alexander Sparrow

BSc (Hons), MSc, PhD

Research Assistant

I work on genetic mutations in troponin and tropomyosin that cause hypertrophic cardiomyopathy (HCM) and dilated cardiomyopathy (DCM). In particular, I work on the development of myofilament specific genetically encoded calcium sensors to study subcellular calcium dynamics in cardiomyocytes. My current research also focuses on the development of novel compounds, which alter calcium sensitivity in cardiomyocytes that can be used to treat the cellular dysfunction in HCM.

I completed my PhD at the University of Nottingham in developmental biology where I studied the role of LIM kinase and metanephric mesenchymal cell migration in the developing kidney.