Cookies on this website
We use cookies to ensure that we give you the best experience on our website. If you click 'Continue' we'll assume that you are happy to receive all cookies and you won't see this message again. Click 'Find out more' for information on how to change your cookie settings.

The origin of an innate ability the brain has to protect itself from damage that occurs in stroke has been explained for the first time. The results, published in Nature Medicine, and led by Prof Alastair Buchan, University of Oxford, demonstrate the important role played by the protein hamartin.

Neurons © Image must be purchased from iStock before use. Filename: 15430_iStock_000006935624Small1_neurons

When deprived of oxygen, some cells in the hippocampus, the part of the brain involved in memory, switch into survival mode and start producing hamartin, which forces the cells to conserve energy. They stop producing new proteins and break down existing ones to access the raw materials. When the cells are prevented from producing hamartin, they die just like other cells.

Read More

We want to hear about your news!

Publishing a paper? Just won an award? Get in touch with


Similar stories

Researchers find genetic ‘fingerprints’ of ancient migrations in modern-day United Arab Emirates

A team of geneticists and archaeologists have analysed the fine-scale genetic structure and ancestry of nearly 1200 people from the United Arab Emirates (UAE), and found genetic traces of population mixing spanning thousands of years.

Study reveals ‘stop-eating’ response to DNA damage

A new study from the Patel Group sheds light on the mechanism by which DNA damage suppresses appetite, a finding with implications for understanding the appetite lowering side-effects of chemotherapy.