Cookies on this website
We use cookies to ensure that we give you the best experience on our website. If you click 'Continue' we'll assume that you are happy to receive all cookies and you won't see this message again. Click 'Find out more' for information on how to change your cookie settings.

The origin of an innate ability the brain has to protect itself from damage that occurs in stroke has been explained for the first time. The results, published in Nature Medicine, and led by Prof Alastair Buchan, University of Oxford, demonstrate the important role played by the protein hamartin.

Neurons © Image must be purchased from iStock before use. Filename: 15430_iStock_000006935624Small1_neurons

When deprived of oxygen, some cells in the hippocampus, the part of the brain involved in memory, switch into survival mode and start producing hamartin, which forces the cells to conserve energy. They stop producing new proteins and break down existing ones to access the raw materials. When the cells are prevented from producing hamartin, they die just like other cells.

Read More

We want to hear about your news!

Publishing a paper? Just won an award? Get in touch with communications@rdm.ox.ac.uk

 

Similar stories

Changes in blood cell production over the human lifetime may hold clues to patterns of disease

A new paper published this week in Cell Reports reveals that changes in the gene expression of blood stem cells occur across the human lifetime; an important step in the understanding and treatment of blood disorders.

Mechanism behind repair of cancer-inducing mutations discovered

New Nature paper uncovers the precise mechanism behind how the BRCA1 protein detects and engages with DNA breaks in the genome, helping to prevent the development of breast and ovarian cancers.

PTH infused insulin pump used as an alternative treatment for young patients with ADH1

Queen Mary University of London and OCDEM researchers develop alternative treatment for patients as young as three months.