Notch signaling: its roles and therapeutic potential in hematological malignancies.
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DLL4 regulates NOTCH signaling and growth of T acute lymphoblastic leukemia cells in NOD/SCID mice.
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Proline-hydroxylated hypoxia-inducible factor 1α (HIF-1α) upregulation in human tumours.
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The notch ligand JAGGED1 as a target for anti-tumor therapy.
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A core human primary tumor angiogenesis signature identifies the endothelial orphan receptor ELTD1 as a key regulator of angiogenesis.
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Molecular basis for Jagged-1/Serrate ligand recognition by the Notch receptor.
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Notch3 signalling promotes tumour growth in colorectal cancer.
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Notch3 signalling promotes tumour growth in colorectal cancer.
Journal article
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Notch3-mediated regulation of MKP-1 levels promotes survival of T acute lymphoblastic leukemia cells.
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Ligand-driven activation of the notch pathway in T-ALL and solid tumors: why Not(ch)?
Journal article
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Cross-talk between tumor and endothelial cells involving the Notch3-Dll4 interaction marks escape from tumor dormancy.
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Hypoxia inducible factor-1alpha inactivation unveils a link between tumor cell metabolism and hypoxia-induced cell death.
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