Publications — Radcliffe Department of Medicine

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Modifying nutritional substrates induces macrovesicular lipid droplet accumulation and metabolic alterations in a cellular model of hepatic steatosis.

Gunn PJ. et al, (2020), Physiol Rep, 8

RSPO3 impacts body fat distribution and regulates adipose cell biology in vitro.

Loh NY. et al, (2020), Nat Commun, 11

Transcriptomic analysis of human primary breast cancer identifies fatty acid oxidation as a target for metformin.

Lord SR. et al, (2019), Br J Cancer

Bone morphogenetic protein 2 is a depot-specific regulator of human adipogenesis.

Denton NF. et al, (2019), Int J Obes (Lond), 43, 2458 - 2468

Correction to: Bone morphogenetic protein 2 is a depot-specific regulator of human adipogenesis.

Denton NF. et al, (2019), Int J Obes (Lond), 43

MicroRNA-196a links human body fat distribution to adipose tissue extracellular matrix composition.

Hilton C. et al, (2019), EBioMedicine

Challenging metabolic tissues with fructose: tissue-specific and sex-specific responses.

Pinnick KE. and Hodson L., (2019), J Physiol

Regional fat depot masses are influenced by protein-coding gene variants

Neville M. et al, (2019)

The circadian clock components BMAL1 and REV-ERBα regulate flavivirus replication.

Zhuang X. et al, (2019), Nat Commun, 10

Measuring Human Lipid Metabolism Using Deuterium Labeling: In Vivo and In Vitro Protocols.

Pinnick KE. et al, (2019), 1862, 83 - 96

Regional fat depot masses are influenced by protein-coding gene variants.

Neville MJ. et al, (2019), PLoS One, 14

Cartilage oligomeric matrix protein is differentially expressed in human subcutaneous adipose tissue and regulates adipogenesis.

Denton N. et al, (2018), Mol Metab, 16, 172 - 179

The diabetes risk gene TCF7L2 regulates human adipose progenitor cell biology

Verma M. et al, (2018), DIABETOLOGIA, 61, S12 - S12

A cellular model for the investigation of depot specific human adipocyte biology.

Todorčević M. et al, (2017), Adipocyte, 6, 40 - 55

Functional evaluation of the human fat distribution HOXC13 gene locus

Kuo F-C. et al, (2016), DIABETOLOGIA, 59, S15 - S16

RSPO3 functions via LGR4 to regulate human body fat distribution by eliciting diverse biological responses in abdominal and gluteal progenitors

Loh NY. et al, (2016), DIABETOLOGIA, 59, S297 - S297

Role of developmental transcription factors in white, brown and beige adipose tissues.

Hilton C. et al, (2015), Biochim Biophys Acta, 1851, 686 - 696

Biology of upper-body and lower-body adipose tissue--link to whole-body phenotypes.

Karpe F. and Pinnick KE., (2015), Nat Rev Endocrinol, 11, 90 - 100

Distinct developmental profile of lower-body adipose tissue defines resistance against obesity-associated metabolic complications.

Pinnick KE. et al, (2014), Diabetes, 63, 3785 - 3797

Fatty acid uptake and lipid storage induced by HIF-1α contribute to cell growth and survival after hypoxia-reoxygenation.

Bensaad K. et al, (2014), Cell Rep, 9, 349 - 365

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