Publications — Radcliffe Department of Medicine

Cookies on this website

We use cookies to ensure that we give you the best experience on our website. If you click 'Continue' we'll assume that you are happy to receive all cookies and you won't see this message again. Click 'Find out more' for information on how to change your cookie settings.

High-resolution targeted 3C interrogation of cis-regulatory element organization at genome-wide scale.

Downes DJ. et al, (2021), Nat Commun, 12

BET inhibition disrupts transcription but retains enhancer-promoter contact.

Crump NT. et al, (2021), Nat Commun, 12

The BET inhibitor CPI203 promotes ex vivo expansion of cord blood long-term repopulating HSCs and megakaryocytes.

Hua P. et al, (2020), Blood, 136, 2410 - 2415

A remarkable case of HbH disease illustrates the relative contributions of the α-globin enhancers to gene expression.

Badat M. et al, (2020), Blood

CaptureCompendium: a comprehensive toolkit for 3C analysis

Telenius J. et al, (2020)

Single-cell analysis of bone marrow-derived CD34+ cells from children with sickle cell disease and thalassemia.

Hua P. et al, (2019), Blood, 134, 2111 - 2115

BET inhibition disrupts transcription but retains enhancer-promoter contact

Crump N. et al, (2019)

An integrated platform to systematically identify causal variants and genes for polygenic human traits

Downes D. et al, (2019)

Scientific Business Abstracts of the 113th Annual Meeting of the Association of Physicians of Great Britain and Ireland.

Cacciottolo TM. et al, (2019), QJM, 112, 724 - 729

The bipartite TAD organization of the X-inactivation center ensures opposing developmental regulation of Tsix and Xist.

van Bemmel JG. et al, (2019), Nat Genet, 51, 1024 - 1034

Single-allele chromatin interactions identify regulatory hubs in dynamic compartmentalized domains.

Oudelaar AM. et al, (2018), Nat Genet, 50, 1744 - 1751

Expression of the Human Alpha-Globin Cluster in the Absence of the Major Regulatory Element Mcs-R2

Badat M. et al, (2018), BLOOD, 132

Macrophage activation syndrome and post-transplant microangiopathy following haploidentical bone marrow transplantation for sickle cell anemia.

Davies JOJ. et al, (2018), Am J Hematol, 93, 588 - 589

HoxC5 and miR-615-3p target newly evolved genomic regions to repress hTERT and inhibit tumorigenesis.

Yan T. et al, (2018), Nat Commun, 9

Robust detection of chromosomal interactions from small numbers of cells using low-input Capture-C.

Oudelaar AM. et al, (2017), Nucleic Acids Res, 45

Low-input Capture-C: A Chromosome Conformation Capture Assay to Analyze Chromatin Architecture in Small Numbers of Cells.

Oudelaar AM. et al, (2017), Bio Protoc, 7

VHL Deficiency Drives Enhancer Activation of Oncogenes in Clear Cell Renal Cell Carcinoma.

Yao X. et al, (2017), Cancer Discov, 7, 1284 - 1305

Comparative analysis of three-dimensional chromosomal architecture identifies a novel fetal hemoglobin regulatory element.

Huang P. et al, (2017), Genes Dev, 31, 1704 - 1713

Gene Therapy in a Patient with Sickle Cell Disease.

Badat M. and Davies J., (2017), N Engl J Med, 376, 2093 - 2094

MLL-AF4 binds directly to a BCL-2 specific enhancer and modulates H3K27 acetylation.

Godfrey L. et al, (2017), Exp Hematol, 47, 64 - 75

Load More

Include forthcoming?