Assessment of Cardiac Energy Metabolism, Function, and Physiology in Patients With Heart Failure Taking Empagliflozin: The Randomized, Controlled EMPA-VISION Trial.
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Compartment‐based Reconstruction of 3D Acquisition‐Weighted 31 P Cardiac MRSI at 7T ‐ a Reproducibility Study
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Developing a metabolic clearance rate framework as a translational analysis approach for hyperpolarized 13C magnetic resonance imaging.
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Reversible pH-responsive MRI contrast with paramagnetic polymer micelles.
Ellis CM. et al, (2023), Chem Commun (Camb)
Cardiometabolic risk factors vary with age differently in females and males
Miller JJ. and Heather LC., (2022), Nature Cardiovascular Research
Direct observation of the molecular mechanism underlying protein polymerization.
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Assessing the effect of anesthetic gas mixtures on hyperpolarized 13 C pyruvate metabolism in the rat brain.
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Functional and Metabolic Imaging in Heart Failure with Preserved Ejection Fraction: Promises, Challenges, and Clinical Utility.
Burrage MK. et al, (2022), Cardiovasc Drugs Ther
Acute intermittent hypoxia drives hepatic de novo lipogenesis in humans and rodents.
Hazlehurst JM. et al, (2022), Metabol Open, 14
Concentration-dependent effects of dichloroacetate in type 2 diabetic hearts assessed by hyperpolarized [1-13 C]-pyruvate magnetic resonance imaging.
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The effects of endogenously- and exogenously-induced hyperketonemia on exercise performance and adaptation.
Dearlove DJ. et al, (2022), Physiol Rep, 10
Promoting high T2 contrast in Dy-doped MSNs through Curie effects.
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A phase 2a trial investigating ninerafaxstat - a novel cardiac mitotrope for the treatment of diabetic cardiomyopathy (IMPROVE-DiCE)
Hundertmark M. et al, (2022), EUROPEAN HEART JOURNAL, 43, 246 - 246
Acidic environments trigger intracellular H+-sensing FAK proteins to re-balance sarcolemmal acid-base transporters and auto-regulate cardiomyocyte pH.
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Energetic Basis for Exercise-Induced Pulmonary Congestion in Heart Failure With Preserved Ejection Fraction.
Burrage MK. et al, (2021), Circulation, 144, 1664 - 1678
Intentional Weight Loss as a Novel Treatment for Heart Failure with Preserved Ejection Fraction
Hundertmark MJ. et al, (2021), CIRCULATION, 144
Myocardial Energetic Impairment is the Basis for Reduced Cardiac Reserve and Exercise-Induced Pulmonary Congestion in Heart Failure With Preserved Ejection Fraction: Insights From Novel Cardiopulmonary Magnetic Resonance Imaging
Burrage MK. et al, (2021), CIRCULATION, 144
A simple, open and extensible gating Control unit for cardiac and respiratory synchronisation control in small animal MRI and demonstration of its robust performance in steady-state maintained CINE-MRI.
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Diabetic mitochondria are resistant to palmitoyl CoA inhibition of respiration, which is detrimental during ischemia.
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