Publications — Radcliffe Department of Medicine

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A single-cell atlas of the human substantia nigra reveals cell-specific pathways associated with neurological disorders

Agarwal D. et al, (2020), Nature Communications, 11

TREM2 Alzheimer's variant R47H causes similar transcriptional dysregulation to knockout, yet only subtle functional phenotypes in human iPSC-derived macrophages.

Hall-Roberts H. et al, (2020), Alzheimers Res Ther, 12

SPAG5 as a prognostic biomarker and chemotherapy sensitivity predictor in breast cancer: a retrospective, integrated genomic, transcriptomic, and protein analysis.

Abdel-Fatah TMA. et al, (2016), Lancet Oncol, 17, 1004 - 1018

MYC functions are specific in biological subtypes of breast cancer and confers resistance to endocrine therapy in luminal tumours.

Green AR. et al, (2016), British journal of cancer, 114, 917 - 928

Camptothecin targets WRN protein: mechanism and relevance in clinical breast cancer.

Shamanna RA. et al, (2016), Oncotarget, 7, 13269 - 13284

RECQL4 helicase has oncogenic potential in sporadic breast cancers.

Arora A. et al, (2016), The Journal of pathology, 238, 495 - 501

HAGE in Triple-Negative Breast Cancer Is a Novel Prognostic, Predictive, and Actionable Biomarker: A Transcriptomic and Protein Expression Analysis.

Abdel-Fatah TMA. et al, (2016), Clinical cancer research : an official journal of the American Association for Cancer Research, 22, 905 - 914

The prognostic significance of STAT3 in invasive breast cancer: analysis of protein and mRNA expressions in large cohorts.

Aleskandarany MA. et al, (2016), Breast cancer research and treatment, 156, 9 - 20

Clinicopathological and prognostic significance of RECQL5 helicase expression in breast cancers.

Arora A. et al, (2016), Carcinogenesis, 37, 63 - 71

Transcriptomic and Protein Expression Analysis Reveals Clinicopathological Significance of Bloom Syndrome Helicase (BLM) in Breast Cancer.

Arora A. et al, (2015), Molecular cancer therapeutics, 14, 1057 - 1065

Untangling the ATR-CHEK1 network for prognostication, prediction and therapeutic target validation in breast cancer.

Abdel-Fatah TMA. et al, (2015), Molecular oncology, 9, 569 - 585

Targeting BRCA1-BER deficient breast cancer by ATM or DNA-PKcs blockade either alone or in combination with cisplatin for personalized therapy.

Albarakati N. et al, (2015), Mol Oncol, 9, 204 - 217

Clinicopathological significance of ATM-Chk2 expression in sporadic breast cancers: a comprehensive analysis in large cohorts.

Abdel-Fatah TMA. et al, (2014), Neoplasia (New York, N.Y.), 16, 982 - 991

Genomic and protein expression analysis reveals flap endonuclease 1 (FEN1) as a key biomarker in breast and ovarian cancer.

Abdel-Fatah TMA. et al, (2014), Mol Oncol, 8, 1326 - 1338

Adverse prognostic and predictive significance of low DNA-dependent protein kinase catalytic subunit (DNA-PKcs) expression in early-stage breast cancers.

Abdel-Fatah T. et al, (2014), Breast cancer research and treatment, 146, 309 - 320

Dissecting DNA repair in adult high grade gliomas for patient stratification in the post-genomic era.

Perry C. et al, (2014), Oncotarget, 5, 5764 - 5781

DNA polymerase β deficiency is linked to aggressive breast cancer: a comprehensive analysis of gene copy number, mRNA and protein expression in multiple cohorts.

Abdel-Fatah TMA. et al, (2014), Mol Oncol, 8, 520 - 532

Single-strand selective monofunctional uracil-DNA glycosylase (SMUG1) deficiency is linked to aggressive breast cancer and predicts response to adjuvant therapy.

Abdel-Fatah TMA. et al, (2013), Breast cancer research and treatment, 142, 515 - 527

Include forthcoming?