Publications — Radcliffe Department of Medicine

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GTP cyclohydrolase drives breast cancer development and promotes EMT in an enzyme-independent manner.

Wang Z. et al, (2023), Cancer Res

Non-Canonical Activin A Signaling Stimulates Context-Dependent and Cellular-Specific Outcomes in CRC to Promote Tumor Cell Migration and Immune Tolerance.

Wiley MB. et al, (2023), Cancers (Basel), 15

Author Correction: Deciphering colorectal cancer genetics through multi-omic analysis of 100,204 cases and 154,587 controls of European and east Asian ancestries.

Fernandez-Rozadilla C. et al, (2023), Nat Genet

Deciphering colorectal cancer genetics through multi-omic analysis of 100,204 cases and 154,587 controls of European and east Asian ancestries.

Fernandez-Rozadilla C. et al, (2022), Nat Genet

CXD101 and nivolumab in patients with metastatic microsatellite-stable colorectal cancer (CAROSELL): a multicentre, open-label, single-arm, phase II trial.

Saunders MP. et al, (2022), ESMO Open, 7

Trends in the Incidence and Mortality of the Most Common Cancers in Iraq (Iraqi Cancer Registry 1999-2019).

Alwan NAS. et al, (2022), Gulf J Oncolog, 1, 47 - 57

A clinical decision support system optimising adjuvant chemotherapy for colorectal cancers by integrating deep learning and pathological staging markers: a development and validation study.

Kleppe A. et al, (2022), Lancet Oncol

The UK benefits from a truly National Health Service.

Barnes E. et al, (2022), Lancet

Cancer in sub-Saharan Africa: a Lancet Oncology Commission.

Ngwa W. et al, (2022), Lancet Oncol

The Influence of Activin on the Tumor Microenvironment in Colon Cancer Metastasis.

Wiley MB. et al, (2022), FASEB J, 36 Suppl 1

Genetic variation in ST6GAL1 is a determinant of capecitabine and oxaliplatin induced hand-foot syndrome.

Watts K. et al, (2022), Int J Cancer

The Essentials of Multiomics.

Marshall JL. et al, (2022), Oncologist, 27, 272 - 284

The Academic Curriculum - Reform Resisted

Kerr D., (2022), 16-19: Changes in Education and Training, 42 - 53

Immune modulation underpins the anti-cancer activity of HDAC inhibitors.

Blaszczak W. et al, (2021), Mol Oncol, 15, 3280 - 3298

Personalising cancer medicine with prognostic markers.

Kerr DJ. and Yang L., (2021), EBioMedicine, 72

Automated assessment of CD8+ T-lymphocytes and stroma fractions complement conventional staging of colorectal cancer.

Jiang D. et al, (2021), EBioMedicine, 71

Novel therapeutic strategies: targeting epithelial-mesenchymal transition in colorectal cancer.

Zhang N. et al, (2021), Lancet Oncol, 22, e358 - e368

A Phase 2a cohort expansion study to assess the safety, tolerability, and preliminary efficacy of CXD101 in patients with advanced solid-organ cancer expressing HR23B or lymphoma.

Booth SW. et al, (2021), BMC Cancer, 21

Genome-wide association studies of toxicity to oxaliplatin and fluoropyrimidine chemotherapy with or without cetuximab in 1800 patients with advanced colorectal cancer.

Watts K. et al, (2021), Int J Cancer

Stromal composition predicts recurrence of early rectal cancer after local excision.

Jones HJ. et al, (2021), Histopathology

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