Clinical significance of preleukemic somatic GATA1 mutations in children with Down syndrome.
Elliott N. et al, (2025), Blood
RUNX1 loss renders hematopoietic and leukemic cells dependent on interleukin-3 and sensitive to JAK inhibition
Fan AC. et al, (2023), Journal of Clinical Investigation
The cell type specific 5hmC landscape and dynamics of healthy human hematopoiesis and TET2-mutant pre-leukemia
Nakauchi Y. et al, (2022), Blood Cancer Discovery
IL-3 SELECTIVELY RESCUES RUNX1-DEFICIENT HUMAN HSPCS WITH DYSREGULATED JAK/STAT SIGNALING
Fan A. et al, (2022), EXPERIMENTAL HEMATOLOGY, 111, S84 - S84
Oncogenic Gata1 causes stage-specific megakaryocyte differentiation delay.
Juban G. et al, (2021), Haematologica, 106, 1106 - 1119
HYPERSENSITIVITY TO IL-3 RESCUES INFLAMMATORY RUNX1-DEFICIENT HUMAN HSPCS
Fan A. et al, (2021), EXPERIMENTAL HEMATOLOGY, 100, S48 - S48
Sensitive, rapid diagnostic test for transient abnormal myelopoiesis and myeloid leukemia of Down syndrome.
Cruz Hernandez D. et al, (2020), Blood, 136, 1460 - 1465
Myeloid Pre-Leukemia and Leukemia of Down Syndrome
Cruz Hernandez D. and VYAS P., (2020), HemaSphere
GATA1 and cooperating mutations in myeloid leukaemia of Down syndrome.
Garnett C. et al, (2020), IUBMB Life, 72, 119 - 130
Oncogenic Drivers and Development.
Cruz Hernandez D. and Vyas P., (2019), Cancer Discov, 9, 1653 - 1655
Mechanisms of Progression of Myeloid Preleukemia to Transformed Myeloid Leukemia in Children with Down Syndrome.
Labuhn M. et al, (2019), Cancer Cell, 36
Mechanisms of Progression of Myeloid Preleukemia to Transformed Myeloid Leukemia in Children with Down Syndrome.
Labuhn M. et al, (2019), Cancer Cell, 36, 123 - 138.e10
MODELING THE PATHOGENESIS OF RUNX1 DEFICIENCY IN INHERITED AML PREDISPOSITION SYNDROMES IN PRIMARY CELLS
Fan A. et al, (2019), EXPERIMENTAL HEMATOLOGY, 76, S65 - S65