Publications

RUNX1 loss renders hematopoietic and leukemic cells dependent on interleukin-3 and sensitive to JAK inhibition

Fan AC. et al, (2023), Journal of Clinical Investigation

Data from The Cell Type–Specific 5hmC Landscape and Dynamics of Healthy Human Hematopoiesis and TET2-Mutant Preleukemia

Nakauchi Y. et al, (2023)

Data from The Cell Type–Specific 5hmC Landscape and Dynamics of Healthy Human Hematopoiesis and TET2-Mutant Preleukemia

Nakauchi Y. et al, (2023)

Supplementary Figure from The Cell Type–Specific 5hmC Landscape and Dynamics of Healthy Human Hematopoiesis and TET2-Mutant Preleukemia

Nakauchi Y. et al, (2023)

Supplementary Figure from The Cell Type–Specific 5hmC Landscape and Dynamics of Healthy Human Hematopoiesis and TET2-Mutant Preleukemia

Nakauchi Y. et al, (2023)

Supplementary Table from The Cell Type–Specific 5hmC Landscape and Dynamics of Healthy Human Hematopoiesis and TET2-Mutant Preleukemia

Nakauchi Y. et al, (2023)

Supplementary Table from The Cell Type–Specific 5hmC Landscape and Dynamics of Healthy Human Hematopoiesis and TET2-Mutant Preleukemia

Nakauchi Y. et al, (2023)

The cell type specific 5hmC landscape and dynamics of healthy human hematopoiesis and TET2-mutant pre-leukemia

Nakauchi Y. et al, (2022), Blood Cancer Discovery

IL-3 SELECTIVELY RESCUES RUNX1-DEFICIENT HUMAN HSPCS WITH DYSREGULATED JAK/STAT SIGNALING

Fan A. et al, (2022), EXPERIMENTAL HEMATOLOGY, 111, S84 - S84

Oncogenic Gata1 causes stage-specific megakaryocyte differentiation delay.

Juban G. et al, (2021), Haematologica, 106, 1106 - 1119

Sensitive, rapid diagnostic test for transient abnormal myelopoiesis and myeloid leukemia of Down syndrome.

Cruz Hernandez D. et al, (2020), Blood, 136, 1460 - 1465

Myeloid Pre-Leukemia and Leukemia of Down Syndrome

Cruz Hernandez D. and VYAS P., (2020), HemaSphere

GATA1 and cooperating mutations in myeloid leukaemia of Down syndrome.

Garnett C. et al, (2020), IUBMB Life, 72, 119 - 130

Oncogenic Drivers and Development.

Cruz Hernandez D. and Vyas P., (2019), Cancer Discov, 9, 1653 - 1655

Mechanisms of Progression of Myeloid Preleukemia to Transformed Myeloid Leukemia in Children with Down Syndrome.

Labuhn M. et al, (2019), Cancer Cell, 36

Mechanisms of Progression of Myeloid Preleukemia to Transformed Myeloid Leukemia in Children with Down Syndrome.

Labuhn M. et al, (2019), Cancer Cell, 36, 123 - 138.e10

Correction: Multiplexed genetic engineering of human hematopoietic stem and progenitor cells using CRISPR/Cas9 and AAV6.

Bak RO. et al, (2018), Elife, 7

Generation and use of a humanized bone-marrow-ossicle niche for hematopoietic xenotransplantation into mice

Reinisch A. et al, (2017), Nature Protocols, 12, 2169 - 2188

Multiplexed genetic engineering of human hematopoietic stem and progenitor cells using CRISPR/Cas9 and AAV6.

Bak RO. et al, (2017), Elife, 6

Multiplexed genetic engineering of human hematopoietic stem and progenitor cells using CRISPR/Cas9 and AAV6

Bak RO. et al, (2017), ELIFE, 6

RUNX1 loss renders hematopoietic and leukemic cells dependent on interleukin-3 and sensitive to JAK inhibition

Data from The Cell Type–Specific 5hmC Landscape and Dynamics of Healthy Human Hematopoiesis and <i>TET2</i>-Mutant Preleukemia

Data from The Cell Type–Specific 5hmC Landscape and Dynamics of Healthy Human Hematopoiesis and <i>TET2</i>-Mutant Preleukemia

Supplementary Figure from The Cell Type–Specific 5hmC Landscape and Dynamics of Healthy Human Hematopoiesis and <i>TET2</i>-Mutant Preleukemia

Supplementary Figure from The Cell Type–Specific 5hmC Landscape and Dynamics of Healthy Human Hematopoiesis and <i>TET2</i>-Mutant Preleukemia

Supplementary Table from The Cell Type–Specific 5hmC Landscape and Dynamics of Healthy Human Hematopoiesis and <i>TET2</i>-Mutant Preleukemia

Supplementary Table from The Cell Type–Specific 5hmC Landscape and Dynamics of Healthy Human Hematopoiesis and <i>TET2</i>-Mutant Preleukemia

The cell type specific 5hmC landscape and dynamics of healthy human hematopoiesis and TET2-mutant pre-leukemia

IL-3 SELECTIVELY RESCUES RUNX1-DEFICIENT HUMAN HSPCS WITH DYSREGULATED JAK/STAT SIGNALING

Oncogenic Gata1 causes stage-specific megakaryocyte differentiation delay.

Sensitive, rapid diagnostic test for transient abnormal myelopoiesis and myeloid leukemia of Down syndrome.

Myeloid Pre-Leukemia and Leukemia of Down Syndrome

GATA1 and cooperating mutations in myeloid leukaemia of Down syndrome.

Oncogenic Drivers and Development.

Mechanisms of Progression of Myeloid Preleukemia to Transformed Myeloid Leukemia in Children with Down Syndrome.

Mechanisms of Progression of Myeloid Preleukemia to Transformed Myeloid Leukemia in Children with Down Syndrome.

Correction: Multiplexed genetic engineering of human hematopoietic stem and progenitor cells using CRISPR/Cas9 and AAV6.

Generation and use of a humanized bone-marrow-ossicle niche for hematopoietic xenotransplantation into mice

Multiplexed genetic engineering of human hematopoietic stem and progenitor cells using CRISPR/Cas9 and AAV6.

Multiplexed genetic engineering of human hematopoietic stem and progenitor cells using CRISPR/Cas9 and AAV6

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