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RUNX1 loss renders hematopoietic and leukemic cells dependent on interleukin-3 and sensitive to JAK inhibition

Journal article

Fan AC. et al, (2023), Journal of Clinical Investigation

IL-3 SELECTIVELY RESCUES RUNX1-DEFICIENT HUMAN HSPCS WITH DYSREGULATED JAK/STAT SIGNALING

Conference paper

Fan A. et al, (2022), EXPERIMENTAL HEMATOLOGY, 111, S84 - S84

Oncogenic Gata1 causes stage-specific megakaryocyte differentiation delay.

Journal article

Juban G. et al, (2021), Haematologica, 106, 1106 - 1119

Sensitive, rapid diagnostic test for transient abnormal myelopoiesis and myeloid leukemia of Down syndrome.

Journal article

Cruz Hernandez D. et al, (2020), Blood, 136, 1460 - 1465

Myeloid Pre-Leukemia and Leukemia of Down Syndrome

Journal article

Cruz Hernandez D. and VYAS P., (2020), HemaSphere

GATA1 and cooperating mutations in myeloid leukaemia of Down syndrome.

Journal article

Garnett C. et al, (2020), IUBMB Life, 72, 119 - 130

Oncogenic Drivers and Development.

Journal article

Cruz Hernandez D. and Vyas P., (2019), Cancer Discov, 9, 1653 - 1655

Generation and use of a humanized bone-marrow-ossicle niche for hematopoietic xenotransplantation into mice

Journal article

Reinisch A. et al, (2017), Nature Protocols, 12, 2169 - 2188

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