Publications — Radcliffe Department of Medicine

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PEPITEM modulates leukocyte trafficking to reduce obesity-induced inflammation.

Pezhman L. et al, (2023), Clin Exp Immunol

Revealing the tissue-level complexity of endogenous glucagon-like peptide-1 receptor expression and signaling.

Ast J. et al, (2023), Nat Commun, 14

GC-globulin/vitamin D-binding protein is Required for Pancreatic α Cell Adaptation to Metabolic Stress.

Viloria K. et al, (2022), Diabetes

Lack of ZnT8 protects pancreatic islets from hypoxia- and cytokine-induced cell death.

Karsai M. et al, (2022), J Endocrinol, 253, 1 - 11

Isoform-specific Roles of Prolyl Hydroxylases in the Regulation of Pancreatic β-Cell Function.

Hoang M. et al, (2022), Endocrinology, 163

Nicotinamide riboside has minimal impact on energy metabolism in mouse models of mild obesity.

Cartwright DM. et al, (2021), The Journal of endocrinology, 251, 111 - 123

Prolyl-4-hydroxylase 3 maintains β cell glucose metabolism during fatty acid excess in mice.

Nasteska D. et al, (2021), JCI Insight, 6

PDX1LOW MAFALOW β-cells contribute to islet function and insulin release.

Nasteska D. et al, (2021), Nat Commun, 12

Persistent or Transient Human β Cell Dysfunction Induced by Metabolic Stress: Specific Signatures and Shared Gene Expression with Type 2 Diabetes.

Marselli L. et al, (2020), Cell reports, 33

Author Correction: Super-resolution microscopy compatible fluorescent probes reveal endogenous glucagon-like peptide-1 receptor distribution and dynamics.

Ast J. et al, (2020), Nat Commun, 11

Maternal hypothyroidism in mice influences glucose metabolism in adult offspring.

Kemkem Y. et al, (2020), Diabetologia, 63, 1822 - 1835

Vitamin-D-Binding Protein Contributes to the Maintenance of α Cell Function and Glucagon Secretion.

Viloria K. et al, (2020), Cell Rep, 31

GPR119 Agonism Revisited: A Novel Target for Increasing β-Cell Mass?

Nasteska D. and Hodson DJ., (2020), Endocrinology, 161

Super-resolution microscopy compatible fluorescent probes reveal endogenous glucagon-like peptide-1 receptor distribution and dynamics.

Ast J. et al, (2020), Nat Commun, 11

The prolyl hydroxylase PHD3 maintains β-cell glucose metabolism during fatty acid excess

Nasteska D. et al, (2020)

Informing β-cell regeneration strategies using studies of heterogeneity.

Nasteska D. et al, (2019), Mol Metab, 27S, S49 - S59

LUXendins reveal endogenous glucagon-like peptide-1 receptor distribution and dynamics

Ast J. et al, (2019)

The role of beta cell heterogeneity in islet function and insulin release.

Nasteska D. and Hodson DJ., (2018), Journal of molecular endocrinology, 61, R43 - R60

Conditional and Reversible Activation of Class A and B G Protein-Coupled Receptors Using Tethered Pharmacology.

Podewin T. et al, (2018), ACS Cent Sci, 4, 166 - 179

Enteral supplementation with glutamine, fiber, and oligosaccharide modulates incretin and glucagon-like peptide-2 secretion.

Joo E. et al, (2015), Journal of diabetes investigation, 6, 302 - 308

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