Publications — Radcliffe Department of Medicine

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Perivascular niche cells sense thrombocytopenia and activate hematopoietic stem cells in an IL-1 dependent manner

Luis TC. et al, (2023), Nature Communications, 14

Loss of endothelial membrane KIT ligand affects systemic KIT ligand levels but not bone marrow hematopoietic stem cells.

Matsuoka S. et al, (2023), Blood, 142, 1622 - 1632

Perivascular niche cells sense thrombocytopenia and activate hematopoietic stem cells in an IL-1 dependent manner.

Luis TC. et al, (2023), Nat Commun, 14

Selective advantage of mutant stem cells in clonal hematopoiesis occurs by attenuating the deleterious effects of inflammation and aging

Jakobsen NA. et al, (2023)

Systemically produced Kit ligand is sufficient to maintain mouse hematopoietic stem cells

NERLOV C. et al, (2023), Blood

Panhematopoietic RNA barcoding enables kinetic measurements of nucleate and anucleate lineages and the activation of myeloid clones following acute platelet depletion.

Wojtowicz EE. et al, (2023), Genome Biol, 24

Epigenetic programming defines haematopoietic stem cell fate restriction.

Meng Y. et al, (2023), Nat Cell Biol

Slow integrin-dependent migration organizes networks of tissue-resident mast cells

Kaltenbach L. et al, (2023), Nature Immunology

Endothelial cell death after ionizing radiation does not impair vascular structure in mouse tumor models.

Kaeppler JR. et al, (2022), EMBO Rep, 23

Author Correction: Myeloid lineage enhancers drive oncogene synergy in CEBPA/CSF3R mutant acute myeloid leukemia.

Braun TP. et al, (2022), Nat Commun, 13

DNMT1 Deficiency Impacts on Plasmacytoid Dendritic Cells in Homeostasis and Autoimmune Disease.

Czeh M. et al, (2022), J Immunol, 208, 358 - 370

3016 – CCR1 AS A POTENTIAL THERAPEUTIC TARGET FOR AML IN THE ELDERLY

Ren X. et al, (2022), Experimental Hematology, 111, S52 - S52

HAEMATOPOIESIS IS AN ORGANIZED PROCESS OF GRADUAL LOSS OF LINEAGE POTENTIALS

Drissen R. and Nerlov C., (2022), EXPERIMENTAL HEMATOLOGY, 111, S82 - S82

To Bi or not to Bi: Acute Erythroid Leukemias and hematopoietic lineage choice.

di Genua C. and Nerlov C., (2021), Exp Hematol

Micro-environmental sensing by bone marrow stroma identifies IL-6 and TGFβ1 as regulators of hematopoietic ageing.

Valletta S. et al, (2020), Nat Commun, 11

Liver haploinsufficiency of RuvBL1 causes hepatic insulin resistance and enhances hepatocellular carcinoma progression.

Mello T. et al, (2020), Int J Cancer, 146, 3410 - 3422

C/EBPα and GATA-2 Mutations Induce Bilineage Acute Erythroid Leukemia through Transformation of a Neomorphic Neutrophil-Erythroid Progenitor.

Di Genua C. et al, (2020), Cancer Cell, 37, 690 - 704.e8

CD34 and EPCR coordinately enrich functional murine hematopoietic stem cells under normal and inflammatory conditions.

Rabe JL. et al, (2020), Exp Hematol, 81, 1 - 15.e6

Single-cell analysis of bone marrow-derived CD34+ cells from children with sickle cell disease and thalassemia.

Hua P. et al, (2019), Blood, 134, 2111 - 2115

Ontogenic Changes in Hematopoietic Hierarchy Determine Pediatric Specificity and Disease Phenotype in Fusion Oncogene-Driven Myeloid Leukemia.

Lopez CK. et al, (2019), Cancer Discov, 9, 1736 - 1753

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