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Hypertrophic cardiomyopathy mutations in MYBPC3 dysregulate myosin.

Journal article

Toepfer CN. et al, (2019), Sci Transl Med, 11

The homozygous K280N troponin T mutation alters cross-bridge kinetics and energetics in human HCM.

Journal article

Piroddi N. et al, (2019), J Gen Physiol, 151, 18 - 29

Mutant Muscle LIM Protein C58G causes cardiomyopathy through protein depletion.

Journal article

Ehsan M. et al, (2018), J Mol Cell Cardiol, 121, 287 - 296

Mammalian γ2 AMPK regulates intrinsic heart rate.

Journal article

Yavari A. et al, (2017), Nat Commun, 8

Activation of Autophagy Ameliorates Cardiomyopathy in Mybpc3-Targeted Knockin Mice.

Journal article

Singh SR. et al, (2017), Circ Heart Fail, 10

Evaluation of MYBPC3 trans-Splicing and Gene Replacement as Therapeutic Options in Human iPSC-Derived Cardiomyocytes.

Journal article

Prondzynski M. et al, (2017), Mol Ther Nucleic Acids, 7, 475 - 486

Aberrant developmental titin splicing and dysregulated sarcomere length in Thymosin β4 knockout mice.

Journal article

Smart N. et al, (2017), J Mol Cell Cardiol, 102, 94 - 107

Does extracellular cardiac troponin I play a pathogenic role independently of autoantibodies?

Journal article

Redwood CS., (2016), Clin Sci (Lond), 130, 2277 - 2278

Chronic Activation of γ2 AMPK Induces Obesity and Reduces β Cell Function.

Journal article

Yavari A. et al, (2016), Cell Metab, 23, 821 - 836

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