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The molecular mechanism of muscle dysfunction associated with the R133W mutation in Tpm2.2.

Journal article

Borovikov YS. et al, (2020), Biochem Biophys Res Commun, 523, 258 - 262

Hypertrophic cardiomyopathy mutations in MYBPC3 dysregulate myosin.

Journal article

Toepfer CN. et al, (2019), Sci Transl Med, 11

The homozygous K280N troponin T mutation alters cross-bridge kinetics and energetics in human HCM.

Journal article

Piroddi N. et al, (2019), J Gen Physiol, 151, 18 - 29

MYBPC3 Mutations Cause Hypertrophic Cardiomyopathy by Dysregulating Myosin: Implications for Therapy

Conference paper

Toepfer CN. et al, (2018), CIRCULATION RESEARCH, 123

Mutant Muscle LIM Protein C58G causes cardiomyopathy through protein depletion.

Journal article

Ehsan M. et al, (2018), J Mol Cell Cardiol, 121, 287 - 296

Mammalian γ2 AMPK regulates intrinsic heart rate.

Journal article

Yavari A. et al, (2017), Nat Commun, 8

Activation of Autophagy Ameliorates Cardiomyopathy in Mybpc3-Targeted Knockin Mice.

Journal article

Singh SR. et al, (2017), Circ Heart Fail, 10

Evaluation of MYBPC3 trans-Splicing and Gene Replacement as Therapeutic Options in Human iPSC-Derived Cardiomyocytes.

Journal article

Prondzynski M. et al, (2017), Mol Ther Nucleic Acids, 7, 475 - 486

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