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A CRISPR/Cas9 genome editing pipeline in the EndoC-βH1 cell line to study genes implicated in beta cell function

Journal article

Grotz AK. et al, (2020), Wellcome Open Research, 4, 150 - 150

Loss of ZnT8 function protects against diabetes by enhanced insulin secretion.

Journal article

Dwivedi OP. et al, (2019), Nat Genet

The transmembrane domain of the SNARE protein VAMP2 is highly sensitive to its lipid environment.

Journal article

Fezoua-Boubegtiten Z. et al, (2019), Biochim Biophys Acta Biomembr, 1861, 670 - 676

Type 2 diabetes risk alleles in PAM impact insulin release from human pancreatic β-cells.

Journal article

Thomsen SK. et al, (2018), Nat Genet, 50, 1122 - 1131

Type-2 Diabetes - A Fusion Pore Disease?

Conference paper

Rorsman P. et al, (2018), BIOPHYSICAL JOURNAL, 114, 10A - 10A

Fusion pore in exocytosis: More than an exit gate? A β-cell perspective.

Journal article

Hastoy B. et al, (2017), Cell Calcium, 68, 45 - 61

The Calcium-Sensing Receptor, a Class C GPCR, Spatially-Directs G-protein Selectivity via Endosomal Signaling.

Conference paper

Gorvin C. et al, (2017), JOURNAL OF BONE AND MINERAL RESEARCH, 32, S8 - S8

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