Vanessa Gregory

Vanessa Gregory is a senior applications programmer for the Diabetes Trials Unit. She is responsible for developing and maintaining the UKPDS Risk Engine, UKPDS Outcomes Model and HOMA calculator. She designs and develops software used internally in DTU, writing multi-user programs for data management, process control and information systems, and assists in the development and maintenance of the DTU network and servers.

Her role also involves implementing custom programming for DTU Trial eCRFs on Medidata Rave. She worked extensively on custom software and systems to support the  ACE trial which was translated into Mandarin and was conducted in China. This included randomisation, medication allocation and site payment systems, and the development of a clinical coding integration.

She joined the DTU in 2008, after 18 years working in the software industry. Her past experience includes development of commercial application software for web design, desktop publishing and risk analysis, on a wide-range of programming systems and platforms. Her specialties are multi-lingual software, implementation of mathematical models and parallel computing. She has a degree from the University of Oxford in mathematics and philosophy.

Development and maintenance of the following DTU software applications.

UKPDS Risk Engine

The UKPDS Risk Engine provides risk estimates and 95% confidence intervals, in individuals with type 2 diabetes not known to have heart disease, for fatal and non-fatal CHD and stroke.

UKPDS Outcomes Model

A computer simulation model for estimating the long-term impact of health interventions for people with type 2 diabetes. It been used in a range of research, clinical and commercial applications worldwide, as well as by NICE.

HOMA 2 Calculator

The HOMA 2 Calculator provides quick and easy access to the HOMA2 model for researchers who wish to use model-derived estimates of steady state beta cell function (%B) and insulin sensitivity (%S).