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Samantha Laber


I received a BSc (Hons) in Biomedical Sciences (Physiology) from the University of Aberdeen (UK) for which I spent one year at the University of British Columbia (Vancouver, Canada). At the Karolinska Institute (Stockholm, Sweden), I studied epigenetic modifications in obese patients before and after Roux-en Y gastric bypass. For my doctoral studies I joined MRC Harwell Institute and the Department of Physiology, Anatomy and Genetics at the University of Oxford. My thesis focused on deciphering the FTO regulatory circuitry in body weight regulation using genetics and genomics approaches. I have previously been awarded a "Young Researcher Prize" from Nature Reviews Endocrinology (2014).

My research areas of interest are primarily the genetics of complex diseases and within this remit I have taken up a Novo Nordisk Postdoctoral Fellowship, which started in October 2017. I will work with Professor Cecilia Lindgren's team at the Big Data Institute (BDI), Li Ka Shing Centre for Health Information and Discovery at the University of Oxford in collaboration with Melina Claussnitzer's group at the Broad Institute of Harvard/MIT. Here I will combine experimental with computational analyses to systematically dissect human genetic risk variants in metabolic diseases. The aim of my work will be to use and develop novel approaches in order to dissect the mechanisms behind non-coding genomic variation in disease risk.