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Contact information

Email
nigel.roberts@imm.ox.ac.uk

Telephone
+44 (0)1865 222390

ORCID
https://orcid.org/0000-0002-5091-3604

Research groups

Hughes Group: Genome Biology

Nigel Roberts

BSc Hons Applied and Human Biology

Hughes Group Lab Manager

NEBOSH qualified
WIMM Health and Safety Committee Minutes Secretary
WIMM Biological Safety Committee Member
WIMM Sustainability Working Group Member

Key publications

Identification of LZTFL1 as a candidate effector gene at a COVID-19 risk locus.

Downes DJ. et al, (2021), Nat Genet, 53, 1606 - 1615

Reactivation of a developmentally silenced embryonic globin gene.

King AJ. et al, (2021), Nat Commun, 12

High-resolution targeted 3C interrogation of cis-regulatory element organization at genome-wide scale.

Downes DJ. et al, (2021), Nat Commun, 12

Targeted high-resolution chromosome conformation capture at genome-wide scale

Downes D. et al, (2020)

Multiplexed analysis of chromosome conformation at vastly improved sensitivity.

Davies JOJ. et al, (2016), Nat Methods, 13, 74 - 80

nalysis of hundreds of cis-regulatory landscapes at high resolution in a single, high-throughput experiment.

Hughes JR. et al, (2014), Nat Genet, 46, 205 - 212

Homozygous mutations in a predicted endonuclease are a novel cause of congenital dyserythropoietic anemia type I.

Babbs C. et al, (2013), Haematologica, 98, 1383 - 1387

Recent publications

ctive regulatory elements recruit cohesin to establish cell specific chromatin domains.

Georgiades E. et al, (2025), Sci Rep, 15

Estimated Doses to the Heart, Lungs and Oesophagus and Risks From Typical UK Radiotherapy for Early Breast Cancer During 2015-2023.

Holt F. et al, (2024), Clin Oncol (R Coll Radiol), 36, e322 - e332

RNA polymerase II pausing temporally coordinates cell cycle progression and erythroid differentiation.

Martell DJ. et al, (2023), Dev Cell, 58, 2112 - 2127.e4

Identification of LZTFL1 as a candidate effector gene at a COVID-19 risk locus.

Downes DJ. et al, (2021), Nat Genet, 53, 1606 - 1615

Reactivation of a developmentally silenced embryonic globin gene.

King AJ. et al, (2021), Nat Commun, 12

Genetic and functional insights into CDA-I prevalence and pathogenesis.

Olijnik A-A. et al, (2021), J Med Genet, 58, 185 - 195

High-resolution targeted 3C interrogation of cis-regulatory element organization at genome-wide scale.

Downes DJ. et al, (2021), Nat Commun, 12

More publications