Dr Nicola Curry
MD FRCP FRCPath
Associate Professor of Haematology
- MRC Clinical Academic Research Partnership Fellow
- Haemostasis Consultant
The role of the endothelium in trauma coagulopathy
Nikki Curry studied medicine at Cambridge. After completing her medical and haematology training in London and Oxford, she studied for her MD with Professor Simon Stanworth at NHS Blood & Transplant, Oxford. She is a Consultant Haematologist with a clinical practice in disorders of bleeding and clotting. Her research focuses on the better understanding of the pathophysiology of trauma coagulopathy and in particular the influence of the endothelium on the evolution of the coagulopathy and the associated bleeding. The aim of her research is to develop to an endothelial model of trauma haemorrhage with a view to improving treatments for major bleeding.
She sits on the UKHCDO Genetics and Gynaecology Working Parties; is the NIHR co-lead for haematology for the Thames Valley; and is a committee member of the British Society of Haemostasis and Thrombosis. She is a co-investigator for a UK wide trauma study: CRYOSTAT-2, evaluating the efficacy of early cryoprecipitate therapy in major trauma haemorrhage.
Key publications
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Non-invasive diagnosis of deep vein thrombosis from ultrasound imaging with machine learning.
Journal article
Kainz B. et al, (2021), NPJ Digit Med, 4
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Viscoelastic haemostatic assay augmented protocols for major trauma haemorrhage (ITACTIC): a randomized, controlled trial.
Journal article
Baksaas-Aasen K. et al, (2021), Intensive Care Med, 47, 49 - 59
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Early fibrinogen concentrate therapy for major haemorrhage in trauma (E-FIT 1): Results from a UK multi-centre, randomised, double blind, placebo-controlled pilot trial
Conference paper
Curry N. et al, (2018), Critical Care, 22
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Haematological management of major haemorrhage: a British Society for Haematology Guideline.
Journal article
Stanworth SJ. et al, (2022), Br J Haematol, 198, 654 - 667
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The European guideline on management of major bleeding and coagulopathy following trauma: sixth edition.
Journal article
Rossaint R. et al, (2023), Crit Care, 27
Recent publications
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Comparative effectiveness of decompressive craniectomy versus craniotomy for traumatic acute subdural hematoma (CENTER-TBI): an observational cohort study.
Journal article
van Essen TA. et al, (2023), EClinicalMedicine, 63
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A new population pharmacokinetic model for recombinant factor IX-Fc fusion concentrate including young children with haemophilia B.
Journal article
Koopman SF. et al, (2023), Br J Clin Pharmacol
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Experimental Models of Traumatic Injuries: Do They Capture the Coagulopathy and Underlying Endotheliopathy Induced by Human Trauma?
Journal article
Barrett L. et al, (2023), Int J Mol Sci, 24
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Platelet factor XIII-A regulates platelet function and promotes clot retraction and stability
Journal article
Mitchell JL. et al, (2023), Research and Practice in Thrombosis and Haemostasis, 7
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A new global fibrinolysis capacity assay for the sensitive detection of hyperfibrinolysis and hypofibrinogenemia in trauma patients.
Journal article
Rossetto A. et al, (2023), J Thromb Haemost