Michael Desborough

• Response to prothrombin complex concentrate to correct acquired abnormalities of the clotting screen in patients with liver impairment.

  Journal article

  Desborough MJR. et al, (2017), Liver Int, 37, 1250 - 1251

• Farnesoid X Receptor and Liver X Receptor Ligands Initiate Formation of Coated Platelets.

  Journal article

  Unsworth AJ. et al, (2017), Arterioscler Thromb Vasc Biol, 37, 1482 - 1493

• Desmopressin use for minimising perioperative blood transfusion.

  Journal article

  Desborough MJ. et al, (2017), Cochrane Database Syst Rev, 7

• The aspirin story - from willow to wonder drug.

  Journal article

  Desborough MJR. and Keeling DM., (2017), Br J Haematol, 177, 674 - 683

• Effect of restrictive versus liberal red cell transfusion strategies on haemostasis: systematic review and meta-analysis.

  Journal article

  Desborough MJR. et al, (2017), Thromb Haemost, 117, 889 - 898

• Restrictive versus liberal blood transfusion for gastrointestinal bleeding: a systematic review and meta-analysis of randomised controlled trials.

  Journal article

  Odutayo A. et al, (2017), Lancet Gastroenterol Hepatol, 2, 354 - 360

• Reversal of direct oral anticoagulants.

  Journal article

  Zhang XY. et al, (2017), Br J Hosp Med (Lond), 78, 165 - 169

• Fibrinogen as an independent predictor of mortality in decompensated cirrhosis and bleeding.

  Journal article

  Desborough MJ. et al, (2017), Hepatology, 65, 1079 - 1080

• Desmopressin for treatment of platelet dysfunction and reversal of antiplatelet agents: a systematic review and meta-analysis of randomized controlled trials.

  Journal article

  Desborough MJ. et al, (2017), J Thromb Haemost, 15, 263 - 272

• Plasma transfusions prior to lumbar punctures and epidural catheters for people with abnormal coagulation

  Journal article

  Estcourt LJ. et al, (2017), Cochrane Database of Systematic Reviews, 2017

• Management of direct oral anticoagulants in women of childbearing potential: guidance from the SSC of the ISTH: comment.

  Journal article

  Desborough MJ. et al, (2017), J Thromb Haemost, 15, 194 - 195

• Alternatives to allogeneic platelet transfusion.

  Journal article

  Desborough MJ. et al, (2016), Br J Haematol, 175, 381 - 392

• Alternative agents to prophylactic platelet transfusion for preventing bleeding in people with thrombocytopenia due to chronic bone marrow failure: a meta-analysis and systematic review.

  Journal article

  Desborough M. et al, (2016), Cochrane Database Syst Rev, 10

• Alternatives, and adjuncts, to prophylactic platelet transfusion for people with haematological malignancies undergoing intensive chemotherapy or stem cell transplantation.

  Journal article

  Desborough M. et al, (2016), Cochrane Database Syst Rev

• Thrombelastography-guided blood product use before invasive procedures in cirrhosis with severe coagulopathy.

  Journal article

  Desborough MJ. and Jairath V., (2016), Hepatology, 64, 682 - 683

• Thrombin generation assay triggered with tissue factor or factor XIa in patients with severe haemophilia A

  Journal article

  Naeem H. et al, (2016), HAEMOPHILIA, 22, 59 - 59

• Patterns of blood component use in cirrhosis: a nationwide study.

  Journal article

  Desborough MJ. et al, (2016), Liver Int, 36, 522 - 529

• Antifibrinolytics (lysine analogues) for the prevention of bleeding in people with haematological disorders.

  Journal article

  Estcourt LJ. et al, (2016), Cochrane Database Syst Rev, 3

• Alternative agents versus prophylactic platelet transfusion for preventing bleeding in patients with thrombocytopenia due to chronic bone marrow failure: a network meta-analysis and systematic review.

  Journal article

  Desborough M. et al, (2016), Cochrane Database Syst Rev, 2016

• Comparison of different platelet transfusion thresholds prior to insertion of central lines in patients with thrombocytopenia.

  Journal article

  Estcourt LJ. et al, (2015), Cochrane Database Syst Rev

• Modern-day management of upper gastrointestinal haemorrhage.

  Journal article

  Jairath V. and Desborough MJ., (2015), Transfus Med, 25, 351 - 357

• Transfusion Threshold Trials: The Need to Establish a Clear Difference in Transfusion Practice between Study Groups.

  Journal article

  Hall SM. and Desborough MJ., (2015), Anesthesiology, 123, 970 - 971

• Fresh frozen plasma for cardiovascular surgery.

  Journal article

  Desborough M. et al, (2015), Cochrane Database Syst Rev

• Comparison of different platelet transfusion thresholds prior to insertion of central lines in patients with thrombocytopenia.

  Journal article

  Estcourt LJ. et al, (2015), Cochrane Database Syst Rev, 2015

• Venous thromboembolism: risk of recurrence and long-term anticoagulation.

  Conference paper

  Khalil L. et al, (2015), Br J Hosp Med (Lond), 76, 72 - 77

• Evaluation of global coagulation profiles in patients with acute severe colitis: Implications for thromboprophylaxis

  Journal article

  Griffiths B. et al, (2015), JOURNAL OF CROHNS & COLITIS, 9, S32 - S32

• Peri-procedural management of bleeding risks in critical care patients: A local audit and national survey

  Journal article

  Hibbs SP. et al, (2015), Journal of the Intensive Care Society, 16, 99 - 104

• Prevention of transfusion-transmitted cytomegalovirus (CMV) infection: Standards of care.

  Journal article

  Lieberman L. et al, (2014), Vox Sang, 107, 276 - 311

• Intravenous immunoglobulin-induced haemolysis: a case report and review of the literature.

  Journal article

  Desborough MJ. et al, (2014), Transfus Med, 24, 219 - 226

• New oral anticoagulants in patients with atrial fibrillation.

  Journal article

  Desborough MJ. and Jairath V., (2014), Lancet, 384

• Is treatment of moderate thrombocytopenia indicated for patients with HCV infection and cirrhosis?

  Journal article

  Desborough MJ. and Jairath V., (2014), Gastroenterology, 147

• RESULTS OF THE UK MULTI-REGIONAL AUDIT OF BLOOD COMPONENT USE IN CIRRHOSIS

  Conference paper

  Jairath V. et al, (2014), GUT, 63, A26 - A26

• Epstein-Barr virus-driven bone marrow aplasia and plasmacytosis mimicking a plasma cell neoplasm.

  Journal article

  Desborough MJ. and Grech H., (2014), Br J Haematol, 165

• Retrospective observational study of interventional radiology and critical care coagulopathy

  Journal article

  Hibbs SP. et al, (2014), Critical Care

• Intravenous immunoglobulin-induced haemolysis: A case report and review of the literature

  Journal article

  Desborough MJ. et al, (2014), Transfusion Medicine, 24, 219 - 226

• Uses and abuses of fresh-frozen plasma for the prophylaxis of bleeding

  Journal article

  Desborough MJ. and Stanworth SJ., (2013), Clinical Medicine, Journal of the Royal College of Physicians of London, 13, 197 - 199

• Uses and abuses of fresh-frozen plasma for the prophylaxis of bleeding.

  Journal article

  Desborough MJ. and Stanworth SJ., (2013), Clin Med (Lond), 13, 197 - 199

• Uses and abuses of fresh frozen plasma for the treatment of bleeding

  Journal article

  Desborough MJ. et al, (2013), Clinical Medicine, Journal of the Royal College of Physicians of London, 13, 200 - 202

• Uses and abuses of fresh frozen plasma for the treatment of bleeding.

  Journal article

  Desborough MJ. et al, (2013), Clin Med (Lond), 13, 200 - 202

• Legal and ethical issues in blood transfusion

  Journal article

  Desborough MJ. and Murphy MF., (2013), British Journal of Hospital Medicine, 74

• Legal and ethical issues in blood transfusion.

  Journal article

  Desborough MJ. and Murphy MF., (2013), Br J Hosp Med (Lond), 74, C2 - C4

• How to interpret a prolonged prothrombin time or activated partial thromboplastin time.

  Journal article

  Desborough MJ. and Keeling DM., (2013), Br J Hosp Med (Lond), 74, C10 - C12

• How to interpret a prolonged prothrombin time or activated partial thromboplastin time.

  Journal article

  Desborough MJ. and Keeling DM., (2013), British journal of hospital medicine (London, England : 2005), 74, C10 - C12

• Plasma transfusion for bedside, radiologically guided, and operating room invasive procedures.

  Journal article

  Desborough M. and Stanworth S., (2012), Transfusion, 52 Suppl 1, 20S - 29S

• Reovirus-mediated cytotoxicity and enhancement of innate immune responses against acute myeloid leukemia.

  Journal article

  Hall K. et al, (2012), Biores Open Access, 1, 3 - 15

• Is otilonium bromide globally effective in irritable bowel syndrome?

  Journal article

  Desborough MJ. and Ford AC., (2011), Aliment Pharmacol Ther, 34, 1034 - 1035

Key Publications

• Desmopressin use for minimising perioperative blood transfusion.

  Journal article

  Desborough MJ. et al, (2017), Cochrane Database Syst Rev, 7

• Desmopressin for treatment of platelet dysfunction and reversal of antiplatelet agents: a systematic review and meta-analysis of randomized controlled trials.

  Journal article

  Desborough MJ. et al, (2017), J Thromb Haemost, 15, 263 - 272

• Restrictive versus liberal blood transfusion for gastrointestinal bleeding: a systematic review and meta-analysis of randomised controlled trials.

  Journal article

  Odutayo A. et al, (2017), Lancet Gastroenterol Hepatol, 2, 354 - 360

• Effect of restrictive versus liberal red cell transfusion strategies on haemostasis: systematic review and meta-analysis.

  Journal article

  Desborough MJR. et al, (2017), Thromb Haemost, 117, 889 - 898

• Alternatives to allogeneic platelet transfusion.

  Journal article

  Desborough MJ. et al, (2016), Br J Haematol, 175, 381 - 392

Recent Publications

• Response to prothrombin complex concentrate to correct acquired abnormalities of the clotting screen in patients with liver impairment.

  Journal article

  Desborough MJR. et al, (2017), Liver Int, 37, 1250 - 1251

• Farnesoid X Receptor and Liver X Receptor Ligands Initiate Formation of Coated Platelets.

  Journal article

  Unsworth AJ. et al, (2017), Arterioscler Thromb Vasc Biol, 37, 1482 - 1493

• Desmopressin use for minimising perioperative blood transfusion.

  Journal article

  Desborough MJ. et al, (2017), Cochrane Database Syst Rev, 7

• The aspirin story - from willow to wonder drug.

  Journal article

  Desborough MJR. and Keeling DM., (2017), Br J Haematol, 177, 674 - 683

• Effect of restrictive versus liberal red cell transfusion strategies on haemostasis: systematic review and meta-analysis.

  Journal article

  Desborough MJR. et al, (2017), Thromb Haemost, 117, 889 - 898