Contact information
Matthew Baxter
BHF CRE Transition Fellow
Research Interests
I am interested in how genes are regulated in health and disease. I combine molecular genomics, computational biology, and machine learning approaches to understand how variations in genome sequence can change cellular phenotypes and lead to complex diseases.
My current work is focused on coronary artery disease. Genome wide association studies have identified hundreds of susceptibility loci, however, the vast majority of variants are located in non-coding genomic regions. I am using chromosome conformation capture technologies and machine learning to understand how these genomic variants cause changes in gene expression which lead to disease.