Dr. Adam Wilkinson
Contact information
Research groups
Adam Wilkinson
MBiochem PhD
Associate Professor of Stem Cell Biology
- KKLF Intermediate Research Fellow
Biography
After completing his undergraduate degree at the University of Oxford, Adam Wilkinson undertook PhD training at the University of Cambridge with Prof. Bertie Gottgens. He then moved to Japan and California to perform postdoctoral training with Prof. Hiromitsu Nakauchi at the University of Tokyo and Stanford University. In 2020, he moved into an Instructor position at the Stanford Institute for Stem Cell Biology and Regenerative Medicine with funding from the US National Institutes of Health (NIH), the Leukemia and Lymphoma Society, and Edward P. Evans Foundation. Most recently, he joined the MRC Molecular Haematology Unit (MRC Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, University of Oxford) as a Group Leader in 2021, supported by funding from the Kay Kendall Leukemia Fund.
Research Summary
The Wilkinson group aims to better understand the biology and translational applications of haematopoietic stem cells (HSCs). HSCs are an adult stem cell population that support life-long blood and immune system function and are also used clinically in stem cell (or bone marrow) transplantation therapies. In particular, the group is interested in developing and applying new ex vivo culture technologies to study healthy and malignant HSCs. The overall goal of this research is to improve treatment options for patients suffering from haematological diseases.
Key publications
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Journal article
Igarashi KJ. et al, (2023), Blood Advances
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Ex Vivo Expansion and Genetic Manipulation of Mouse Hematopoietic Stem Cells in Polyvinyl Alcohol-Based Cultures
Journal article
Khoo HM. et al, (2022), Journal of Visualized Experiments
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Journal article
Bozhilov YK. et al, (2023), Cells, 12
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Journal article
Sakurai M. et al, (2023), Nature, 615, 127 - 133
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Journal article
Wilkinson AC. et al, (2021), Nat Commun, 12
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Journal article
Wilkinson AC. et al, (2019), Nature, 571, 117 - 121
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Journal article
Wilkinson AC. et al, (2020), Nat Protoc, 15, 628 - 648
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Journal article
Nishimura T. et al, (2019), Exp Hematol, 80, 16 - 20
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Journal article
Wilkinson AC. et al, (2020), Nat Rev Genet, 21, 541 - 554