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Immune activation is often associated with inflammation, but inflammation's role in the expansion of antigen-specific immune responses remains unclear. This primer focuses on recent findings that show how specific natural killer T cells are activated by inflammatory messengers, thus illuminating the cellular and molecular links between immunity and inflammation.

Original publication

DOI

10.1371/journal.pbio.1000226

Type

Journal article

Journal

PLoS Biol

Publication Date

10/2009

Volume

7

Keywords

Animals, Antigen Presentation, Antigens, CD1d, Autoimmunity, Humans, Inflammation, Lymphocyte Activation, Lysophosphatidylcholines, Natural Killer T-Cells